CDCA8

Cell division cycle associated 8
Identifiers
Symbols	CDCA8 ; BOR; FLJ10468; FLJ12042
External IDs	Template:OMIM5 Template:MGI HomoloGene: 23075
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Cell division cycle associated 8, also known as CDCA8, is a human gene.

CDCA8 is a component of a chromosomal passenger complex required for stability of the bipolar mitotic spindle (Gassmann et al., 2004).[supplied by OMIM]

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Walker MG (2002). "Drug target discovery by gene expression analysis: cell cycle genes". Current cancer drug targets. 1 (1): 73–83. PMID 12188893.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gassmann R, Carvalho A, Henzing AJ; et al. (2004). "Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle". J. Cell Biol. 166 (2): 179–91. doi:10.1083/jcb.200404001. PMID 15249581.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sampath SC, Ohi R, Leismann O; et al. (2004). "The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly". Cell. 118 (2): 187–202. doi:10.1016/j.cell.2004.06.026. PMID 15260989.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sauer G, Körner R, Hanisch A; et al. (2005). "Proteome analysis of the human mitotic spindle". Mol. Cell Proteomics. 4 (1): 35–43. doi:10.1074/mcp.M400158-MCP200. PMID 15561729.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Andersen JS, Lam YW, Leung AK; et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vader G, Kauw JJ, Medema RH, Lens SM (2006). "Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody". EMBO Rep. 7 (1): 85–92. doi:10.1038/sj.embor.7400562. PMID 16239925.CS1 maint: Multiple names: authors list (link)
• Noton EA, Colnaghi R, Tate S; et al. (2006). "Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis". J. Biol. Chem. 281 (2): 1286–95. doi:10.1074/jbc.M508773200. PMID 16291752.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chang JL, Chen TH, Wang CF; et al. (2006). "Borealin/Dasra B is a cell cycle-regulated chromosomal passenger protein and its nuclear accumulation is linked to poor prognosis for human gastric cancer". Exp. Cell Res. 312 (7): 962–73. doi:10.1016/j.yexcr.2005.12.015. PMID 16427043.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lens SM, Rodriguez JA, Vader G; et al. (2006). "Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres". Mol. Biol. Cell. 17 (4): 1897–909. doi:10.1091/mbc.E05-08-0727. PMID 16436504.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rodriguez JA, Lens SM, Span SW; et al. (2006). "Subcellular localization and nucleocytoplasmic transport of the chromosomal passenger proteins before nuclear envelope breakdown". Oncogene. 25 (35): 4867–79. doi:10.1038/sj.onc.1209499. PMID 16547492.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nousiainen M, Silljé HH, Sauer G; et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMID 16565220.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Klein UR, Nigg EA, Gruneberg U (2006). "Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP". Mol. Biol. Cell. 17 (6): 2547–58. doi:10.1091/mbc.E05-12-1133. PMID 16571674.CS1 maint: Multiple names: authors list (link)
• Kaur H, Stiff AC, Date DA, Taylor WR (2007). "Analysis of mitotic phosphorylation of borealin". BMC Cell Biol. 8: 5. doi:10.1186/1471-2121-8-5. PMID 17241471.CS1 maint: Multiple names: authors list (link)
• Hayama S, Daigo Y, Yamabuki T; et al. (2007). "Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis". Cancer Res. 67 (9): 4113–22. doi:10.1158/0008-5472.CAN-06-4705. PMID 17483322.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)