CHAF1A

Chromatin assembly factor 1, subunit A (p150)
Identifiers
Symbols	CHAF1A ; CAF-1; CAF1; CAF1B; CAF1P150; MGC71229; P150
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4003
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Chromatin assembly factor 1, subunit A (p150), also known as CHAF1A, is a human gene.

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995).[supplied by OMIM]

Further reading

• Ridgway P, Almouzni G (2000). "CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair". J. Cell. Sci. 113 ( Pt 15): 2647–58. PMID 10893180.
• Kaufman PD, Kobayashi R, Kessler N, Stillman B (1995). "The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication". Cell. 81 (7): 1105–14. PMID 7600578.CS1 maint: Multiple names: authors list (link)
• Verreault A, Kaufman PD, Kobayashi R, Stillman B (1996). "Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4". Cell. 87 (1): 95–104. PMID 8858152.CS1 maint: Multiple names: authors list (link)
• Marheineke K, Krude T (1998). "Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle". J. Biol. Chem. 273 (24): 15279–86. PMID 9614144.
• Shibahara K, Stillman B (1999). "Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin". Cell. 96 (4): 575–85. PMID 10052459.
• Murzina N, Verreault A, Laue E, Stillman B (1999). "Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins". Mol. Cell. 4 (4): 529–40. PMID 10549285.CS1 maint: Multiple names: authors list (link)
• Moggs JG, Grandi P, Quivy JP; et al. (2000). "A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage". Mol. Cell. Biol. 20 (4): 1206–18. PMID 10648606.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lechner MS, Begg GE, Speicher DW, Rauscher FJ (2000). "Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential". Mol. Cell. Biol. 20 (17): 6449–65. PMID 10938122.CS1 maint: Multiple names: authors list (link)
• Dong H, Lin W, Zhang CK; et al. (2001). "Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene". Gene. 264 (2): 187–96. PMID 11250073.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mello JA, Silljé HH, Roche DM; et al. (2002). "Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway". EMBO Rep. 3 (4): 329–34. doi:10.1093/embo-reports/kvf068. PMID 11897662.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Reese BE, Bachman KE, Baylin SB, Rountree MR (2003). "The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1". Mol. Cell. Biol. 23 (9): 3226–36. PMID 12697822.CS1 maint: Multiple names: authors list (link)
• Morel AP, Sentis S, Bianchin C; et al. (2004). "BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms". J. Cell. Sci. 116 (Pt 14): 2929–36. doi:10.1242/jcs.00480. PMID 12771185.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kitagawa H, Fujiki R, Yoshimura K; et al. (2003). "The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome". Cell. 113 (7): 905–17. PMID 12837248.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Glinsky GV, Glinskii AB, Stephenson AJ; et al. (2004). "Gene expression profiling predicts clinical outcome of prostate cancer". J. Clin. Invest. 113 (6): 913–23. doi:10.1172/JCI200420032. PMID 15067324.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jiao R, Bachrati CZ, Pedrazzi G; et al. (2004). "Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1". Mol. Cell. Biol. 24 (11): 4710–9. doi:10.1128/MCB.24.11.4710-4719.2004. PMID 15143166.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMID 15231747.
• Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sarraf SA, Stancheva I (2004). "Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly". Mol. Cell. 15 (4): 595–605. doi:10.1016/j.molcel.2004.06.043. PMID 15327775.