CUL5

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Cullin 5
Identifiers
Symbols CUL5 ; VACM-1; VACM1
External IDs Template:OMIM5 Template:MGI HomoloGene2597
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Cullin 5, also known as CUL5, is a human gene.[1]


References

  1. "Entrez Gene: CUL5 cullin 5".

Further reading

  • Kipreos ET, Lander LE, Wing JP; et al. (1996). "cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family". Cell. 85 (6): 829–39. PMID 8681378.
  • Hillier LD, Lennon G, Becker M; et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. PMID 8889549.
  • Byrd PJ, Stankovic T, McConville CM; et al. (1997). "Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23". Genome Res. 7 (1): 71–5. PMID 9037604.
  • Stankovic T, Byrd PJ, Cooper PR; et al. (1997). "Construction of a transcription map around the gene for ataxia telangiectasia: identification of at least four novel genes". Genomics. 40 (2): 267–76. doi:10.1006/geno.1996.4595. PMID 9119394.
  • North WG, Fay MJ, Longo KA, Du J (1998). "Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide". Cancer Res. 58 (9): 1866–71. PMID 9581826.
  • Burnatowska-Hledin M, Lazdins IB, Listenberger L; et al. (1999). "VACM-1 receptor is specifically expressed in rabbit vascular endothelium and renal collecting tubule". Am. J. Physiol. 276 (2 Pt 2): F199–209. PMID 9950950.
  • Wada H, Yeh ET, Kamitani T (1999). "Identification of NEDD8-conjugation site in human cullin-2". Biochem. Biophys. Res. Commun. 257 (1): 100–5. doi:10.1006/bbrc.1999.0339. PMID 10092517.
  • Ohta T, Michel JJ, Schottelius AJ, Xiong Y (1999). "ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity". Mol. Cell. 3 (4): 535–41. PMID 10230407.
  • Hori T, Osaka F, Chiba T; et al. (2000). "Covalent modification of all members of human cullin family proteins by NEDD8". Oncogene. 18 (48): 6829–34. doi:10.1038/sj.onc.1203093. PMID 10597293.
  • Burnatowska-Hledin M, Zhao P, Capps B; et al. (2000). "VACM-1, a cullin gene family member, regulates cellular signaling". Am. J. Physiol., Cell Physiol. 279 (1): C266–73. PMID 10898738.
  • Kamura T, Burian D, Yan Q; et al. (2001). "Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase". J. Biol. Chem. 276 (32): 29748–53. doi:10.1074/jbc.M103093200. PMID 11384984.
  • Burnatowska-Hledin , Zeneberg A, Roulo A; et al. (2001). "Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycle". Endothelium. 8 (1): 49–63. PMID 11409851.
  • Harada JN, Shevchenko A, Shevchenko A; et al. (2002). "Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery". J. Virol. 76 (18): 9194–206. PMID 12186903.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Liu J, Furukawa M, Matsumoto T, Xiong Y (2003). "NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases". Mol. Cell. 10 (6): 1511–8. PMID 12504025.
  • Van Dort C, Zhao P, Parmelee K; et al. (2004). "VACM-1, a cul-5 gene, inhibits cellular growth by a mechanism that involves MAPK and p53 signaling pathways". Am. J. Physiol., Cell Physiol. 285 (6): C1386–96. doi:10.1152/ajpcell.00338.2002. PMID 12917106.
  • Yu X, Yu Y, Liu B; et al. (2003). "Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex". Science. 302 (5647): 1056–60. doi:10.1126/science.1089591. PMID 14564014.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Burnatowska-Hledin MA, Kossoris JB, Van Dort CJ; et al. (2004). "T47D breast cancer cell growth is inhibited by expression of VACM-1, a cul-5 gene". Biochem. Biophys. Res. Commun. 319 (3): 817–25. doi:10.1016/j.bbrc.2004.05.057. PMID 15184056.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.

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