DAPP1

Dual adaptor of phosphotyrosine and 3-phosphoinositides
PDB rendering based on 1fao.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1fao​, 1fb8​
Identifiers
Symbols	DAPP1 ; BAM32; DKFZp667E0716
External IDs	Template:OMIM5 Template:MGI HomoloGene: 32138
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Dual adaptor of phosphotyrosine and 3-phosphoinositides, also known as DAPP1, is a human gene.

Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.CS1 maint: Multiple names: authors list (link)
• Dowler S, Currie RA, Downes CP, Alessi DR (1999). "DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides". Biochem. J. 342 ( Pt 1): 7–12. PMID 10432293.CS1 maint: Multiple names: authors list (link)
• Marshall AJ, Niiro H, Lerner CG; et al. (2000). "A novel B lymphocyte-associated adaptor protein, Bam32, regulates antigen receptor signaling downstream of phosphatidylinositol 3-kinase". J. Exp. Med. 191 (8): 1319–32. PMID 10770799.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dowler S, Montalvo L, Cantrell D; et al. (2001). "Phosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinase". Biochem. J. 349 (Pt 2): 605–10. PMID 10880360.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ferguson KM, Kavran JM, Sankaran VG; et al. (2000). "Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains". Mol. Cell. 6 (2): 373–84. PMID 10983984.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dowler S, Currie RA, Campbell DG; et al. (2001). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities". Biochem. J. 351 (Pt 1): 19–31. PMID 11001876.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang QH, Ye M, Wu XY; et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. PMID 11042152.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Stephens LR, Anderson KE, Hawkins PT (2001). "Src family kinases mediate receptor-stimulated, phosphoinositide 3-kinase-dependent, tyrosine phosphorylation of dual adaptor for phosphotyrosine and 3-phosphoinositides-1 in endothelial and B cell lines". J. Biol. Chem. 276 (46): 42767–73. doi:10.1074/jbc.M107194200. PMID 11524430.CS1 maint: Multiple names: authors list (link)
• Niiro H, Maeda A, Kurosaki T, Clark EA (2002). "The B lymphocyte adaptor molecule of 32 kD (Bam32) regulates B cell antigen receptor signaling and cell survival". J. Exp. Med. 195 (1): 143–9. PMID 11781373.CS1 maint: Multiple names: authors list (link)
• Marshall AJ, Krahn AK, Ma K; et al. (2002). "TAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptor". Mol. Cell. Biol. 22 (15): 5479–91. PMID 12101241.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Han A, Saijo K, Mecklenbräuker I; et al. (2003). "Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival". Immunity. 19 (4): 621–32. PMID 14563325.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Allam A, Niiro H, Clark EA, Marshall AJ (2004). "The adaptor protein Bam32 regulates Rac1 activation and actin remodeling through a phosphorylation-dependent mechanism". J. Biol. Chem. 279 (38): 39775–82. doi:10.1074/jbc.M403367200. PMID 15247305.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Niiro H, Allam A, Stoddart A; et al. (2004). "The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization". J. Immunol. 173 (9): 5601–9. PMID 15494510.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)