DLK1

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Delta-like 1 homolog (Drosophila)
Identifiers
Symbols DLK1 ; FA1; PREF1; Pref-1; ZOG; pG2
External IDs Template:OMIM5 Template:MGI HomoloGene2846
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Delta-like 1 homolog (Drosophila), also known as DLK1, is a human gene.[1]


References

  1. "Entrez Gene: DLK1 delta-like 1 homolog (Drosophila)".

Further reading

  • Helman LJ, Sack N, Plon SE, Israel MA (1990). "The sequence of an adrenal specific human cDNA, pG2". Nucleic Acids Res. 18 (3): 685. PMID 2308864.
  • Helman LJ, Thiele CJ, Linehan WM; et al. (1987). "Molecular markers of neuroendocrine development and evidence of environmental regulation". Proc. Natl. Acad. Sci. U.S.A. 84 (8): 2336–9. PMID 3470797.
  • Lee YL, Helman L, Hoffman T, Laborda J (1995). "dlk, pG2 and Pref-1 mRNAs encode similar proteins belonging to the EGF-like superfamily. Identification of polymorphic variants of this RNA". Biochim. Biophys. Acta. 1261 (2): 223–32. PMID 7711066.
  • Jensen CH, Krogh TN, Højrup P; et al. (1994). "Protein structure of fetal antigen 1 (FA1). A novel circulating human epidermal-growth-factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2". Eur. J. Biochem. 225 (1): 83–92. PMID 7925474.
  • Laborda J, Sausville EA, Hoffman T, Notario V (1993). "dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line". J. Biol. Chem. 268 (6): 3817–20. PMID 8095043.
  • Smas CM, Sul HS (1993). "Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation". Cell. 73 (4): 725–34. PMID 8500166.
  • Jensen CH, Teisner B, Højrup P; et al. (1993). "Studies on the isolation, structural analysis and tissue localization of fetal antigen 1 and its relation to a human adrenal-specific cDNA, pG2". Hum. Reprod. 8 (4): 635–41. PMID 8501199.
  • Tornehave D, Jensen CH, Teisner B, Larsson LI (1997). "FA1 immunoreactivity in endocrine tumours and during development of the human fetal pancreas; negative correlation with glucagon expression". Histochem. Cell Biol. 106 (6): 535–42. PMID 8985741.
  • Jensen CH, Schroder HD, Teisner B; et al. (2000). "Fetal antigen 1, a member of the epidermal growth factor superfamily, in neurofibromas and serum from patients with neurofibromatosis type 1". Br. J. Dermatol. 140 (6): 1054–9. PMID 10354070.
  • Gubina E, Ruiz-Hidalgo MJ, Baladrón V, Laborda J (1999). "Assignment of DLK1 to human chromosome band 14q32 by in situ hybridization". Cytogenet. Cell Genet. 84 (3–4): 206–7. PMID 10393432.
  • Jensen CH, Erb K, Westergaard LG; et al. (1999). "Fetal antigen 1, an EGF multidomain protein in the sex hormone-producing cells of the gonads and the microenvironment of germ cells". Mol. Hum. Reprod. 5 (10): 908–13. PMID 10508217.
  • Aguan K, Carvajal JA, Thompson LP, Weiner CP (2001). "Application of a functional genomics approach to identify differentially expressed genes in human myometrium during pregnancy and labour". Mol. Hum. Reprod. 6 (12): 1141–5. PMID 11101697.
  • Andersen M, Jensen CH, Støving RK; et al. (2001). "Fetal antigen 1 in healthy adults and patients with pituitary disease: relation to physiological, pathological, and pharmacological GH levels". J. Clin. Endocrinol. Metab. 86 (11): 5465–70. PMID 11701723.
  • Jensen CH, Meyer M, Schroder HD; et al. (2002). "Neurons in the monoaminergic nuclei of the rat and human central nervous system express FA1/dlk". Neuroreport. 12 (18): 3959–63. PMID 11742219.
  • Baladrón V, Ruiz-Hidalgo MJ, Bonvini E; et al. (2002). "The EGF-like homeotic protein dlk affects cell growth and interacts with growth-modulating molecules in the yeast two-hybrid system". Biochem. Biophys. Res. Commun. 291 (2): 193–204. doi:10.1006/bbrc.2002.6431. PMID 11846389.
  • Panin VM, Shao L, Lei L; et al. (2002). "Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe". J. Biol. Chem. 277 (33): 29945–52. doi:10.1074/jbc.M204445200. PMID 12036964.
  • Doggett KL, Briggs JA, Linton MF; et al. (2002). "Retroviral mediated expression of the human myeloid nuclear antigen in a null cell line upregulates Dlk1 expression". J. Cell. Biochem. 86 (1): 56–66. doi:10.1002/jcb.10190. PMID 12112016.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Van Limpt VA, Chan AJ, Van Sluis PG; et al. (2003). "High delta-like 1 expression in a subset of neuroblastoma cell lines corresponds to a differentiated chromaffin cell type". Int. J. Cancer. 105 (1): 61–9. doi:10.1002/ijc.11047. PMID 12672031.
  • Abdallah BM, Jensen CH, Gutierrez G; et al. (2004). "Regulation of human skeletal stem cells differentiation by Dlk1/Pref-1". J. Bone Miner. Res. 19 (5): 841–52. doi:10.1359/JBMR.040118. PMID 15068508.

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