Dopachrome tautomerase

Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)
Identifiers
Symbols	DCT ; TYRP2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 1447
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene.

Further reading

• Jackson IJ, Chambers DM, Tsukamoto K; et al. (1992). "A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus". EMBO J. 11 (2): 527–35. PMID 1537334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tobin D, Quinn AG, Ito S, Thody AJ (1995). "The presence of tyrosinase and related proteins in human epidermis and their relationship to melanin type". Pigment Cell Res. 7 (4): 204–9. PMID 7855064.CS1 maint: Multiple names: authors list (link)
• Bernd A, Ramirez-Bosca A, Kippenberger S; et al. (1995). "Levels of dopachrome tautomerase in human melanocytes cultured in vitro". Melanoma Res. 4 (5): 287–91. PMID 7858411.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yokoyama K, Yasumoto K, Suzuki H, Shibahara S (1994). "Cloning of the human DOPAchrome tautomerase/tyrosinase-related protein 2 gene and identification of two regulatory regions required for its pigment cell-specific expression". J. Biol. Chem. 269 (43): 27080–7. PMID 7929451.CS1 maint: Multiple names: authors list (link)
• Orlow SJ, Zhou BK, Chakraborty AK; et al. (1994). "High-molecular-weight forms of tyrosinase and the tyrosinase-related proteins: evidence for a melanogenic complex". J. Invest. Dermatol. 103 (2): 196–201. PMID 8040609.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sturm RA, Baker E, Sutherland GR (1994). "Assignment of the tyrosinase-related protein-2 gene (TYRP2) to human chromosome 13q31-q32 by fluorescence in situ hybridization: extended synteny with mouse chromosome 14". Genomics. 21 (1): 293–6. doi:10.1006/geno.1994.1266. PMID 8088811.CS1 maint: Multiple names: authors list (link)
• Abdel-Malek Z, Swope V, Collins C; et al. (1994). "Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes". J. Cell. Sci. 106 ( Pt 4): 1323–31. PMID 8126111.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yokoyama K, Suzuki H, Yasumoto K; et al. (1994). "Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2". Biochim. Biophys. Acta. 1217 (3): 317–21. PMID 8148378.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cassady JL, Sturm RA (1994). "Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA". Gene. 143 (2): 295–8. PMID 8206391.
• Odh G, Hindemith A, Rosengren AM; et al. (1994). "Isolation of a new tautomerase monitored by the conversion of D-dopachrome to 5,6-dihydroxyindole". Biochem. Biophys. Res. Commun. 197 (2): 619–24. doi:10.1006/bbrc.1993.2524. PMID 8267597.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bouchard B, Del Marmol V, Jackson IJ; et al. (1994). "Molecular characterization of a human tyrosinase-related-protein-2 cDNA. Patterns of expression in melanocytic cells". Eur. J. Biochem. 219 (1–2): 127–34. PMID 8306979.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sturm RA, O'Sullivan BJ, Box NF; et al. (1996). "Chromosomal structure of the human TYRP1 and TYRP2 loci and comparison of the tyrosinase-related protein gene family". Genomics. 29 (1): 24–34. doi:10.1006/geno.1995.1211. PMID 8530077.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Björk P, Aman P, Hindemith A; et al. (1996). "A new enzyme activity in human blood cells and isolation of the responsible protein (D-dopachrome tautomerase) from erythrocytes". Eur. J. Haematol. 57 (3): 254–6. PMID 8898931.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Smith-Thomas L, Richardson P, Thody AJ; et al. (1997). "Human ocular melanocytes and retinal pigment epithelial cells differ in their melanogenic properties in vivo and in vitro". Curr. Eye Res. 15 (11): 1079–91. PMID 8950502.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang RF, Appella E, Kawakami Y; et al. (1997). "Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes". J. Exp. Med. 184 (6): 2207–16. PMID 8976176.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chi DD, Merchant RE, Rand R; et al. (1997). "Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas". Am. J. Pathol. 150 (6): 2143–52. PMID 9176405.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sugimoto H, Taniguchi M, Nakagawa A; et al. (1997). "Crystallization and preliminary X-ray analysis of human D-dopachrome tautomerase". J. Struct. Biol. 120 (1): 105–8. doi:10.1006/jsbi.1997.3904. PMID 9356298.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nishihira J, Fujinaga M, Kuriyama T; et al. (1998). "Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation". Biochem. Biophys. Res. Commun. 243 (2): 538–44. doi:10.1006/bbrc.1998.8123. PMID 9480844.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kippenberger S, Loitsch S, Solano F; et al. (1998). "Quantification of tyrosinase, TRP-1, and Trp-2 transcripts in human melanocytes by reverse transcriptase-competitive multiplex PCR--regulation by steroid hormones". J. Invest. Dermatol. 110 (4): 364–7. doi:10.1046/j.1523-1747.1998.00144.x. PMID 9540976.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lupetti R, Pisarra P, Verrecchia A; et al. (1998). "Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage". J. Exp. Med. 188 (6): 1005–16. PMID 9743519.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)