ELL (gene)

Elongation factor RNA polymerase II
PDB rendering based on 2doa.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2doa​
Identifiers
Symbols	ELL ; C19orf17; DKFZp434I1916; ELL1; Men
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4762
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Elongation factor RNA polymerase II, also known as ELL, is a human gene.

Further reading

• Thirman MJ, Levitan DA, Kobayashi H; et al. (1995). "Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia". Proc. Natl. Acad. Sci. U.S.A. 91 (25): 12110–4. PMID 7991593.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Iwabuchi K, Bartel PL, Li B; et al. (1994). "Two cellular proteins that bind to wild-type but not mutant p53". Proc. Natl. Acad. Sci. U.S.A. 91 (13): 6098–102. PMID 8016121.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Shilatifard A, Lane WS, Jackson KW; et al. (1996). "An RNA polymerase II elongation factor encoded by the human ELL gene". Science. 271 (5257): 1873–6. PMID 8596958.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shilatifard A, Haque D, Conaway RC, Conaway JW (1997). "Structure and function of RNA polymerase II elongation factor ELL. Identification of two overlapping ELL functional domains that govern its interaction with polymerase and the ternary elongation complex". J. Biol. Chem. 272 (35): 22355–63. PMID 9268387.CS1 maint: Multiple names: authors list (link)
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shilatifard A (1998). "Identification and purification of the Holo-ELL complex. Evidence for the presence of ELL-associated proteins that suppress the transcriptional inhibitory activity of ELL". J. Biol. Chem. 273 (18): 11212–7. PMID 9556611.
• Li XY, Green MR (1998). "The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor". Genes Dev. 12 (19): 2992–6. PMID 9765201.
• Shinobu N, Maeda T, Aso T; et al. (1999). "Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53". J. Biol. Chem. 274 (24): 17003–10. PMID 10358050.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Schmidt AE, Miller T, Schmidt SL; et al. (1999). "Cloning and characterization of the EAP30 subunit of the ELL complex that confers derepression of transcription by RNA polymerase II". J. Biol. Chem. 274 (31): 21981–5. PMID 10419521.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kim MK, Nikodem VM (2000). "hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation". Mol. Cell. Biol. 19 (10): 6833–44. PMID 10490622.
• Lavau C, Luo RT, Du C, Thirman MJ (2000). "Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice". Proc. Natl. Acad. Sci. U.S.A. 97 (20): 10984–9. doi:10.1073/pnas.190167297. PMID 10995463.CS1 maint: Multiple names: authors list (link)
• Wiemann S, Weil B, Wellenreuther R; et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Simone F, Polak PE, Kaberlein JJ; et al. (2001). "EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein". Blood. 98 (1): 201–9. PMID 11418481.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Luo RT, Lavau C, Du C; et al. (2001). "The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis". Mol. Cell. Biol. 21 (16): 5678–87. doi:10.1128/MCB.21.16.5678-5687.2001. PMID 11463848.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Simone F, Luo RT, Polak PE; et al. (2003). "ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties". Blood. 101 (6): 2355–62. doi:10.1182/blood-2002-06-1664. PMID 12446457.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Polak PE, Simone F, Kaberlein JJ; et al. (2003). "ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia". Mol. Biol. Cell. 14 (4): 1517–28. doi:10.1091/mbc.E02-07-0394. PMID 12686606.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wiederschain D, Kawai H, Gu J; et al. (2003). "Molecular basis of p53 functional inactivation by the leukemic protein MLL-ELL". Mol. Cell. Biol. 23 (12): 4230–46. PMID 12773566.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)