FGF13

Fibroblast growth factor 13
Identifiers
Symbols	FGF13 ; FGF2; FHF2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3036
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Fibroblast growth factor 13, also known as FGF13, is a human gene.

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located to a region associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a syndromal X-linked mental retardation, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has not yet been determined. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Further reading

• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wittmack EK, Rush AM, Craner MJ; et al. (2005). "Fibroblast growth factor homologous factor 2B: association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons". J. Neurosci. 24 (30): 6765–75. doi:10.1523/JNEUROSCI.1628-04.2004. PMID 15282281.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Popovici C, Conchonaud F, Birnbaum D, Roubin R (2004). "Functional phylogeny relates LET-756 to fibroblast growth factor 9". J. Biol. Chem. 279 (38): 40146–52. doi:10.1074/jbc.M405795200. PMID 15199049.CS1 maint: Multiple names: authors list (link)
• Facchiano A, Russo K, Facchiano AM; et al. (2003). "Identification of a novel domain of fibroblast growth factor 2 controlling its angiogenic properties". J. Biol. Chem. 278 (10): 8751–60. doi:10.1074/jbc.M209936200. PMID 12496262.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Schoorlemmer J, Goldfarb M (2003). "Fibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinase". J. Biol. Chem. 277 (51): 49111–9. doi:10.1074/jbc.M205520200. PMID 12244047.
• Knox S, Merry C, Stringer S; et al. (2002). "Not all perlecans are created equal: interactions with fibroblast growth factor (FGF) 2 and FGF receptors". J. Biol. Chem. 277 (17): 14657–65. doi:10.1074/jbc.M111826200. PMID 11847221.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Munoz-Sanjuan I, Smallwood PM, Nathans J (2000). "Isoform diversity among fibroblast growth factor homologous factors is generated by alternative promoter usage and differential splicing". J. Biol. Chem. 275 (4): 2589–97. PMID 10644718.CS1 maint: Multiple names: authors list (link)
• Gecz J, Baker E, Donnelly A; et al. (1999). "Fibroblast growth factor homologous factor 2 (FHF2): gene structure, expression and mapping to the Börjeson-Forssman-Lehmann syndrome region in Xq26 delineated by a duplication breakpoint in a BFLS-like patient". Hum. Genet. 104 (1): 56–63. PMID 10071193.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yao DL, Masonic K, Petullo D; et al. (1999). "Pretreatment with intravenous FGF-13 reduces infarct volume and ameliorates neurological deficits following focal cerebral ischemia in rats". Brain Res. 818 (1): 140–6. PMID 9914447.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Greene JM, Li YL, Yourey PA; et al. (1998). "Identification and characterization of a novel member of the fibroblast growth factor family". Eur. J. Neurosci. 10 (5): 1911–25. PMID 9751161.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Smallwood PM, Munoz-Sanjuan I, Tong P; et al. (1996). "Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development". Proc. Natl. Acad. Sci. U.S.A. 93 (18): 9850–7. PMID 8790420.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)