FZR1

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Fizzy/cell division cycle 20 related 1 (Drosophila)
Identifiers
Symbols FZR1 ; CDH1; CDC20C; FZR; FZR2; HCDH; HCDH1; KIAA1242
External IDs Template:OMIM5 Template:MGI HomoloGene9444
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Fizzy/cell division cycle 20 related 1 (Drosophila), also known as FZR1, is a human gene.[1]


References

  1. "Entrez Gene: FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)".

Further reading

  • Fang G, Yu H, Kirschner MW (1998). "Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1". Mol. Cell. 2 (2): 163–71. PMID 9734353.
  • Kramer ER, Gieffers C, Hölzl G; et al. (1999). "Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family". Curr. Biol. 8 (22): 1207–10. PMID 9811605.
  • Kotani S, Tanaka H, Yasuda H, Todokoro K (1999). "Regulation of APC activity by phosphorylation and regulatory factors". J. Cell Biol. 146 (4): 791–800. PMID 10459014.
  • Gieffers C, Peters BH, Kramer ER; et al. (1999). "Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons". Proc. Natl. Acad. Sci. U.S.A. 96 (20): 11317–22. PMID 10500174.
  • Nagase T, Ishikawa K, Kikuno R; et al. (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. PMID 10574462.
  • Sorensen CS, Lukas C, Kramer ER; et al. (2000). "Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis". Mol. Cell. Biol. 20 (20): 7613–23. PMID 11003657.
  • Bembenek J, Yu H (2002). "Regulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14a". J. Biol. Chem. 276 (51): 48237–42. doi:10.1074/jbc.M108126200. PMID 11598127.
  • Stroschein SL, Bonni S, Wrana JL, Luo K (2001). "Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN". Genes Dev. 15 (21): 2822–36. doi:10.1101/gad.912901. PMID 11691834.
  • Hsu JY, Reimann JD, Sørensen CS; et al. (2002). "E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)". Nat. Cell Biol. 4 (5): 358–66. doi:10.1038/ncb785. PMID 11988738.
  • Zur A, Brandeis M (2002). "Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes". EMBO J. 21 (17): 4500–10. PMID 12198152.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Zhou Y, Ching YP, Chun AC, Jin DY (2003). "Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation". J. Biol. Chem. 278 (14): 12530–6. doi:10.1074/jbc.M212853200. PMID 12560341.
  • Zhou Y, Ching YP, Ng RW, Jin DY (2003). "Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1". Biochem. J. 374 (Pt 2): 349–58. doi:10.1042/BJ20030600. PMID 12797865.
  • Vodermaier HC, Gieffers C, Maurer-Stroh S; et al. (2004). "TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1". Curr. Biol. 13 (17): 1459–68. PMID 12956947.
  • Wei W, Ayad NG, Wan Y; et al. (2004). "Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex". Nature. 428 (6979): 194–8. doi:10.1038/nature02381. PMID 15014503.
  • Listovsky T, Oren YS, Yudkovsky Y; et al. (2005). "Mammalian Cdh1/Fzr mediates its own degradation". EMBO J. 23 (7): 1619–26. doi:10.1038/sj.emboj.7600149. PMID 15029244.
  • Grimwood J, Gordon LA, Olsen A; et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
  • Nourry C, Maksumova L, Pang M; et al. (2005). "Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1". BMC Cell Biol. 5: 20. doi:10.1186/1471-2121-5-20. PMID 15144564.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Kraft C, Vodermaier HC, Maurer-Stroh S; et al. (2005). "The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates". Mol. Cell. 18 (5): 543–53. doi:10.1016/j.molcel.2005.04.023. PMID 15916961.

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