GSPT1

G1 to S phase transition 1
Identifiers
Symbols	GSPT1 ; 551G9.2; ETF3A; GST1; eRF3a
External IDs	Template:OMIM5 Template:MGI HomoloGene: 68226
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

G1 to S phase transition 1, also known as GSPT1, is a human gene.

Further reading

• Ozawa K, Murakami Y, Eki T; et al. (1992). "Mapping of the human GSPT1 gene, a human homolog of the yeast GST1 gene, to chromosomal band 16p13.1". Somat. Cell Mol. Genet. 18 (2): 189–94. PMID 1574740.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hoshino S, Miyazawa H, Enomoto T; et al. (1990). "A human homologue of the yeast GST1 gene codes for a GTP-binding protein and is expressed in a proliferation-dependent manner in mammalian cells". EMBO J. 8 (12): 3807–14. PMID 2511002.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kikuchi Y, Shimatake H, Kikuchi A (1988). "A yeast gene required for the G1-to-S transition encodes a protein containing an A-kinase target site and GTPase domain". EMBO J. 7 (4): 1175–82. PMID 2841115.CS1 maint: Multiple names: authors list (link)
• Czaplinski K, Ruiz-Echevarria MJ, Paushkin SV; et al. (1998). "The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs". Genes Dev. 12 (11): 1665–77. PMID 9620853.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hoshino S, Imai M, Mizutani M; et al. (1998). "Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1". J. Biol. Chem. 273 (35): 22254–9. PMID 9712840.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Merkulova TI, Frolova LY, Lazar M; et al. (1999). "C-terminal domains of human translation termination factors eRF1 and eRF3 mediate their in vivo interaction". FEBS Lett. 443 (1): 41–7. PMID 9928949.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hoshino S, Imai M, Kobayashi T; et al. (1999). "The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein". J. Biol. Chem. 274 (24): 16677–80. PMID 10358005.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Loftus BJ, Kim UJ, Sneddon VP; et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cosson B, Berkova N, Couturier A; et al. (2003). "Poly(A)-binding protein and eRF3 are associated in vivo in human and Xenopus cells". Biol. Cell. 94 (4–5): 205–16. PMID 12489690.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hegde R, Srinivasula SM, Datta P; et al. (2003). "The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein". J. Biol. Chem. 278 (40): 38699–706. doi:10.1074/jbc.M303179200. PMID 12865429.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Janzen DM, Geballe AP (2004). "The effect of eukaryotic release factor depletion on translation termination in human cell lines". Nucleic Acids Res. 32 (15): 4491–502. doi:10.1093/nar/gkh791. PMID 15326224.
• Le Roy F, Salehzada T, Bisbal C; et al. (2005). "A newly discovered function for RNase L in regulating translation termination". Nat. Struct. Mol. Biol. 12 (6): 505–12. doi:10.1038/nsmb944. PMID 15908960.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brito M, Malta-Vacas J, Carmona B; et al. (2006). "Polyglycine expansions in eRF3/GSPT1 are associated with gastric cancer susceptibility". Carcinogenesis. 26 (12): 2046–9. doi:10.1093/carcin/bgi168. PMID 15987717.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chauvin C, Salhi S, Le Goff C; et al. (2005). "Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation". Mol. Cell. Biol. 25 (14): 5801–11. doi:10.1128/MCB.25.14.5801-5811.2005. PMID 15987998.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kashima I, Yamashita A, Izumi N; et al. (2006). "Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay". Genes Dev. 20 (3): 355–67. doi:10.1101/gad.1389006. PMID 16452507.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tompkins V, Hagen J, Zediak VP, Quelle DE (2006). "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle. 5 (6): 641–6. PMID 16582619.CS1 maint: Multiple names: authors list (link)
• Lim J, Hao T, Shaw C; et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chauvin C, Salhi S, Jean-Jean O (2007). "Human eukaryotic release factor 3a depletion causes cell cycle arrest at G1 phase through inhibition of the mTOR pathway". Mol. Cell. Biol. 27 (16): 5619–29. doi:10.1128/MCB.00035-07. PMID 17562865.CS1 maint: Multiple names: authors list (link)