HPR (gene)
| Haptoglobin-related protein | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | HPR ; HP; A-259H10.2 | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 8273 | ||||||||||
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| RNA expression pattern | |||||||||||
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| File:PBB GE HPR 208470 s at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Haptoglobin-related protein, also known as HPR, is a human gene.[1]
References
Further reading
- Erickson LM, Kim HS, Maeda N (1993). "Junctions between genes in the haptoglobin gene cluster of primates". Genomics. 14 (4): 948–58. PMID 1478675.
- Maeda N, McEvoy SM, Harris HF; et al. (1986). "Polymorphisms in the human haptoglobin gene cluster: chromosomes with multiple haptoglobin-related (Hpr) genes". Proc. Natl. Acad. Sci. U.S.A. 83 (19): 7395–9. PMID 2876426.
- Maeda N (1985). "Nucleotide sequence of the haptoglobin and haptoglobin-related gene pair. The haptoglobin-related gene contains a retrovirus-like element". J. Biol. Chem. 260 (11): 6698–709. PMID 2987228.
- Bensi G, Raugei G, Klefenz H, Cortese R (1985). "Structure and expression of the human haptoglobin locus". EMBO J. 4 (1): 119–26. PMID 4018023.
- Smith AB, Esko JD, Hajduk SL (1995). "Killing of trypanosomes by the human haptoglobin-related protein". Science. 268 (5208): 284–6. PMID 7716520.
- Hillier LD, Lennon G, Becker M; et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. PMID 8889549.
- Tabak S, Lev A, Valansi C; et al. (1997). "Transcriptionally active haptoglobin-related (Hpr) gene in hepatoma G2 and leukemia molt-4 cells". DNA Cell Biol. 15 (11): 1001–7. PMID 8945641.
- Muranjan M, Nussenzweig V, Tomlinson S (1998). "Characterization of the human serum trypanosome toxin, haptoglobin-related protein". J. Biol. Chem. 273 (7): 3884–7. PMID 9461571.
- Raper J, Fung R, Ghiso J; et al. (1999). "Characterization of a novel trypanosome lytic factor from human serum". Infect. Immun. 67 (4): 1910–6. PMID 10085035.
- Loftus BJ, Kim UJ, Sneddon VP; et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
- Xu XR, Huang J, Xu ZG; et al. (2002). "Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver". Proc. Natl. Acad. Sci. U.S.A. 98 (26): 15089–94. doi:10.1073/pnas.241522398. PMID 11752456.
- Hatada S, Seed JR, Barker C; et al. (2002). "No trypanosome lytic activity in the sera of mice producing human haptoglobin-related protein". Mol. Biochem. Parasitol. 119 (2): 291–4. PMID 11814582.
- Nielsen MJ, Petersen SV, Jacobsen C; et al. (2006). "Haptoglobin-related protein is a high-affinity hemoglobin-binding plasma protein". Blood. 108 (8): 2846–9. doi:10.1182/blood-2006-05-022327. PMID 16778136.
- Vanhollebeke B, Nielsen MJ, Watanabe Y; et al. (2007). "Distinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serum". Proc. Natl. Acad. Sci. U.S.A. 104 (10): 4118–23. doi:10.1073/pnas.0609902104. PMID 17360487.
- Widener J, Nielsen MJ, Shiflett A; et al. (2007). "Hemoglobin is a co-factor of human trypanosome lytic factor". PLoS Pathog. 3 (9): 1250–61. doi:10.1371/journal.ppat.0030129. PMID 17845074.
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