HSPB2
Heat shock 27kDa protein 2 | |||||||||||
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Identifiers | |||||||||||
Symbols | HSPB2 ; HSP27; Hs.78846; MGC133245; MKBP | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 68189 | ||||||||||
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RNA expression pattern | |||||||||||
More reference expression data | |||||||||||
Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
Heat shock 27kDa protein 2, also known as HSPB2, is a human gene.[1]
References
Further reading
- Concannon CG, Gorman AM, Samali A (2003). "On the role of Hsp27 in regulating apoptosis". Apoptosis. 8 (1): 61–70. PMID 12510153.
- Elisei R, Weightman D, Kendall-Taylor P; et al. (1993). "Muscle autoantigens in thyroid associated ophthalmopathy: the limits of molecular genetics". J. Endocrinol. Invest. 16 (7): 533–40. PMID 8227983.
- Iwaki A, Nagano T, Nakagawa M; et al. (1998). "Identification and characterization of the gene encoding a new member of the alpha-crystallin/small hsp family, closely linked to the alphaB-crystallin gene in a head-to-head manner". Genomics. 45 (2): 386–94. doi:10.1006/geno.1997.4956. PMID 9344664.
- Suzuki A, Sugiyama Y, Hayashi Y; et al. (1998). "MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase". J. Cell Biol. 140 (5): 1113–24. PMID 9490724.
- Deak M, Clifton AD, Lucocq LM, Alessi DR (1998). "Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB". EMBO J. 17 (15): 4426–41. doi:10.1093/emboj/17.15.4426. PMID 9687510.
- Sugiyama Y, Suzuki A, Kishikawa M; et al. (2000). "Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation". J. Biol. Chem. 275 (2): 1095–104. PMID 10625651.
- Baysal BE, Willett-Brozick JE, Taschner PE; et al. (2001). "A high-resolution integrated map spanning the SDHD gene at 11q23: a 1.1-Mb BAC contig, a partial transcript map and 15 new repeat polymorphisms in a tumour-suppressor region". Eur. J. Hum. Genet. 9 (2): 121–9. doi:10.1038/sj.ejhg.5200585. PMID 11313745.
- Nakagawa M, Tsujimoto N, Nakagawa H; et al. (2001). "Association of HSPB2, a member of the small heat shock protein family, with mitochondria". Exp. Cell Res. 271 (1): 161–8. doi:10.1006/excr.2001.5362. PMID 11697892.
- Ito H, Kamei K, Iwamoto I; et al. (2002). "Inhibition of proteasomes induces accumulation, phosphorylation, and recruitment of HSP27 and alphaB-crystallin to aggresomes". J. Biochem. 131 (4): 593–603. PMID 11926998.
- Boxman IL, Kempenaar J, de Haas E, Ponec M (2003). "Induction of HSP27 nuclear immunoreactivity during stress is modulated by vitamin C.". Exp. Dermatol. 11 (6): 509–17. PMID 12473058.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Patel VM, Heinel LA, Provencio JJ; et al. (2003). "Validation of image analysis for enzyme histochemical and immunocytochemical staining". Biotechnic & histochemistry : official publication of the Biological Stain Commission. 77 (4): 213–21. PMID 12503731.
- Mao H, Li F, Ruchalski K; et al. (2003). "hsp72 inhibits focal adhesion kinase degradation in ATP-depleted renal epithelial cells". J. Biol. Chem. 278 (20): 18214–20. doi:10.1074/jbc.M300126200. PMID 12611892.
- Yonekura N, Yokota S, Yonekura K; et al. (2003). "Interferon-gamma downregulates Hsp27 expression and suppresses the negative regulation of cell death in oral squamous cell carcinoma lines". Cell Death Differ. 10 (3): 313–22. doi:10.1038/sj.cdd.4401169. PMID 12700631.
- Kantham L, Kerr-Bayles L, Godde N; et al. (2003). "Beacon interacts with cdc2/cdc28-like kinases". Biochem. Biophys. Res. Commun. 304 (1): 125–9. PMID 12705895.
- Yaglom J, O'Callaghan-Sunol C, Gabai V, Sherman MY (2003). "Inactivation of dual-specificity phosphatases is involved in the regulation of extracellular signal-regulated kinases by heat shock and hsp72". Mol. Cell. Biol. 23 (11): 3813–24. PMID 12748284.
- Park KJ, Gaynor RB, Kwak YT (2003). "Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activation". J. Biol. Chem. 278 (37): 35272–8. doi:10.1074/jbc.M305095200. PMID 12829720.
- Wen FC, Li YH, Tsai HF; et al. (2003). "Down-regulation of heat shock protein 27 in neuronal cells and non-neuronal cells expressing mutant ataxin-3". FEBS Lett. 546 (2–3): 307–14. PMID 12832059.
- Parcellier A, Schmitt E, Gurbuxani S; et al. (2003). "HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation". Mol. Cell. Biol. 23 (16): 5790–802. PMID 12897149.
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