HTATIP2

HIV-1 Tat interactive protein 2, 30kDa
PDB rendering based on 2bka.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2bka​, 2fmu​
Identifiers
Symbols	HTATIP2 ; CC3; TIP30
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4676
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

HIV-1 Tat interactive protein 2, 30kDa, also known as HTATIP2, is a human gene. It may be a metastasis suppressor.

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Shtivelman E (1997). "A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma". Oncogene. 14 (18): 2167–73. doi:10.1038/sj.onc.1201059. PMID 9174052.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xiao H, Tao Y, Greenblatt J, Roeder RG (1998). "A cofactor, TIP30, specifically enhances HIV-1 Tat-activated transcription". Proc. Natl. Acad. Sci. U.S.A. 95 (5): 2146–51. PMID 9482853.CS1 maint: Multiple names: authors list (link)
• Baker ME (1999). "TIP30, a cofactor for HIV-1 Tat-activated transcription, is homologous to short-chain dehydrogenases/reductases". Curr. Biol. 9 (13): R471. PMID 10395547.
• Whitman S, Wang X, Shalaby R, Shtivelman E (2000). "Alternatively spliced products CC3 and TC3 have opposing effects on apoptosis". Mol. Cell. Biol. 20 (2): 583–93. PMID 10611237.CS1 maint: Multiple names: authors list (link)
• Xiao H, Palhan V, Yang Y, Roeder RG (2000). "TIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes". EMBO J. 19 (5): 956–63. doi:10.1093/emboj/19.5.956. PMID 10698937.CS1 maint: Multiple names: authors list (link)
• Baker ME, Yan L, Pear MR (2000). "Three-dimensional model of human TIP30, a coactivator for HIV-1 Tat-activated transcription, and CC3, a protein associated with metastasis suppression". Cell. Mol. Life Sci. 57 (5): 851–8. PMID 10892349.CS1 maint: Multiple names: authors list (link)
• NicAmhlaoibh R, Shtivelman E (2001). "Metastasis suppressor CC3 inhibits angiogenic properties of tumor cells in vitro". Oncogene. 20 (2): 270–5. doi:10.1038/sj.onc.1204075. PMID 11313954.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ito M, Jiang C, Krumm K; et al. (2004). "TIP30 deficiency increases susceptibility to tumorigenesis". Cancer Res. 63 (24): 8763–7. PMID 14695192.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jiang C, Ito M, Piening V; et al. (2004). "TIP30 interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates c-myc transcription". J. Biol. Chem. 279 (26): 27781–9. doi:10.1074/jbc.M401809200. PMID 15073177.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tsutsumi S, Kamata N, Vokes TJ; et al. (2004). "The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD)". Am. J. Hum. Genet. 74 (6): 1255–61. doi:10.1086/421527. PMID 15124103.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• King FW, Shtivelman E (2004). "Inhibition of nuclear import by the proapoptotic protein CC3". Mol. Cell. Biol. 24 (16): 7091–101. doi:10.1128/MCB.24.16.7091-7101.2004. PMID 15282309.
• Suzuki Y, Yamashita R, Shirota M; et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sun L, Feng S, Reséndiz JC; et al. (2005). "Role of the Pyk2-MAP kinase-cPLA2 signaling pathway in shear-dependent platelet aggregation". Annals of biomedical engineering. 32 (9): 1193–201. PMID 15493507.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shi M, Zhang X, Wang P; et al. (2005). "TIP30 regulates apoptosis-related genes in its apoptotic signal transduction pathway". World J. Gastroenterol. 11 (2): 221–7. PMID 15633220.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• El Omari K, Bird LE, Nichols CE; et al. (2005). "Crystal structure of CC3 (TIP30): implications for its role as a tumor suppressor". J. Biol. Chem. 280 (18): 18229–36. doi:10.1074/jbc.M501113200. PMID 15728189.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Caldwell RL, Lane KB, Shepherd VL (2006). "HIV-1 Tat interaction with cyclin T1 represses mannose receptor and the bone morphogenetic protein receptor-2 transcription". Arch. Biochem. Biophys. 449 (1–2): 27–33. doi:10.1016/j.abb.2006.02.020. PMID 16615932.CS1 maint: Multiple names: authors list (link)