IGFALS

Insulin-like growth factor binding protein, acid labile subunit
Identifiers
Symbols	IGFALS ; ALS
External IDs	Template:OMIM5 Template:MGI HomoloGene: 37987
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Insulin-like growth factor binding protein, acid labile subunit, also known as IGFALS, is a human gene.

Further reading

• Domené HM, Bengolea SV, Jasper HG, Boisclair YR (2005). "Acid-labile subunit deficiency: phenotypic similarities and differences between human and mouse". J. Endocrinol. Invest. 28 (5 Suppl): 43–6. PMID 16114275.CS1 maint: Multiple names: authors list (link)
• Leong SR, Baxter RC, Camerato T; et al. (1992). "Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex". Mol. Endocrinol. 6 (6): 870–6. PMID 1379671.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dai J, Baxter RC (1992). "Molecular cloning of the acid-labile subunit of the rat insulin-like growth factor binding protein complex". Biochem. Biophys. Res. Commun. 188 (1): 304–9. PMID 1384485.
• Baxter RC, Martin JL, Beniac VA (1989). "High molecular weight insulin-like growth factor binding protein complex. Purification and properties of the acid-labile subunit from human serum". J. Biol. Chem. 264 (20): 11843–8. PMID 2473065.CS1 maint: Multiple names: authors list (link)
• Firth SM, Ganeshprasad U, Baxter RC (1998). "Structural determinants of ligand and cell surface binding of insulin-like growth factor-binding protein-3". J. Biol. Chem. 273 (5): 2631–8. PMID 9446566.CS1 maint: Multiple names: authors list (link)
• Twigg SM, Baxter RC (1998). "Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit". J. Biol. Chem. 273 (11): 6074–9. PMID 9497324.
• Twigg SM, Kiefer MC, Zapf J, Baxter RC (1998). "Insulin-like growth factor-binding protein 5 complexes with the acid-labile subunit. Role of the carboxyl-terminal domain". J. Biol. Chem. 273 (44): 28791–8. PMID 9786878.CS1 maint: Multiple names: authors list (link)
• Suwanichkul A, Boisclair YR, Olney RC; et al. (2000). "Conservation of a growth hormone-responsive promoter element in the human and mouse acid-labile subunit genes". Endocrinology. 141 (2): 833–8. PMID 10650966.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ueki I, Ooi GT, Tremblay ML; et al. (2000). "Inactivation of the acid labile subunit gene in mice results in mild retardation of postnatal growth despite profound disruptions in the circulating insulin-like growth factor system". Proc. Natl. Acad. Sci. U.S.A. 97 (12): 6868–73. doi:10.1073/pnas.120172697. PMID 10823924.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Suzuki H, Fukunishi Y, Kagawa I; et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs". Genome Res. 11 (10): 1758–65. doi:10.1101/gr.180101. PMID 11591653.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sneppen SB, Lange M, Pedersen LM; et al. (2002). "Total and free insulin-like growth factor I, insulin-like growth factor binding protein 3 and acid-labile subunit reflect clinical activity in acromegaly". Growth Horm. IGF Res. 11 (6): 384–91. doi:10.1054/ghir.2001.0254. PMID 11914026.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cisternino M, Draghi M, Lauriola S; et al. (2002). "The acid-labile subunit of human ternary insulin-like growth factor-binding protein complex in girls with central precocious puberty before and during gonadotropin-releasing hormone analog therapy". J. Clin. Endocrinol. Metab. 87 (10): 4629–33. PMID 12364447.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Anderson NL, Polanski M, Pieper R; et al. (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources". Mol. Cell Proteomics. 3 (4): 311–26. doi:10.1074/mcp.M300127-MCP200. PMID 14718574.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Domené HM, Bengolea SV, Martínez AS; et al. (2004). "Deficiency of the circulating insulin-like growth factor system associated with inactivation of the acid-labile subunit gene". N. Engl. J. Med. 350 (6): 570–7. doi:10.1056/NEJMoa013100. PMID 14762184.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Payet LD, Firth SM, Baxter RC (2004). "The role of the acid-labile subunit in regulating insulin-like growth factor transport across human umbilical vein endothelial cell monolayers". J. Clin. Endocrinol. Metab. 89 (5): 2382–9. PMID 15126567.CS1 maint: Multiple names: authors list (link)
• Martin J, Han C, Gordon LA; et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16". Nature. 432 (7020): 988–94. doi:10.1038/nature03187. PMID 15616553.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu T, Qian WJ, Gritsenko MA; et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Deming SL, Ren Z, Wen W; et al. (2007). "Genetic variation in IGF1, IGF-1R, IGFALS, and IGFBP3 in breast cancer survival among Chinese women: a report from the Shanghai Breast Cancer Study". Breast Cancer Res. Treat. 104 (3): 309–19. doi:10.1007/s10549-006-9420-8. PMID 17063263.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)