IGFBP6

Insulin-like growth factor binding protein 6
PDB rendering based on 2jm2.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2jm2​
Identifiers
Symbols	IGFBP6 ; IBP6
External IDs	Template:OMIM5 Template:MGI HomoloGene: 1641
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Insulin-like growth factor binding protein 6, also known as IGFBP6, is a human gene.

Further reading

• Wood AW, Duan C, Bern HA (2005). "Insulin-like growth factor signaling in fish". Int. Rev. Cytol. 243: 215–85. doi:10.1016/S0074-7696(05)43004-1. PMID 15797461.CS1 maint: Multiple names: authors list (link)
• Zapf J, Kiefer M, Merryweather J; et al. (1990). "Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia". J. Biol. Chem. 265 (25): 14892–8. PMID 1697583.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kiefer MC, Masiarz FR, Bauer DM, Zapf J (1991). "Identification and molecular cloning of two new 30-kDa insulin-like growth factor binding proteins isolated from adult human serum". J. Biol. Chem. 266 (14): 9043–9. PMID 1709161.CS1 maint: Multiple names: authors list (link)
• Shimasaki S, Gao L, Shimonaka M, Ling N (1991). "Isolation and molecular cloning of insulin-like growth factor-binding protein-6". Mol. Endocrinol. 5 (7): 938–48. PMID 1719383.CS1 maint: Multiple names: authors list (link)
• Andress DL, Birnbaum RS (1991). "A novel human insulin-like growth factor binding protein secreted by osteoblast-like cells". Biochem. Biophys. Res. Commun. 176 (1): 213–8. PMID 1850257.
• Kiefer MC, Ioh RS, Bauer DM, Zapf J (1991). "Molecular cloning of a new human insulin-like growth factor binding protein". Biochem. Biophys. Res. Commun. 176 (1): 219–25. PMID 1850258.CS1 maint: Multiple names: authors list (link)
• Martin JL, Willetts KE, Baxter RC (1990). "Purification and properties of a novel insulin-like growth factor-II binding protein from transformed human fibroblasts". J. Biol. Chem. 265 (7): 4124–30. PMID 2154495.CS1 maint: Multiple names: authors list (link)
• Roghani M, Hossenlopp P, Lepage P; et al. (1989). "Isolation from human cerebrospinal fluid of a new insulin-like growth factor-binding protein with a selective affinity for IGF-II". FEBS Lett. 255 (2): 253–8. PMID 2551732.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ilvesmäki V, Blum WF, Voutilainen R (1994). "Insulin-like growth factor binding proteins in the human adrenal gland". Mol. Cell. Endocrinol. 97 (1–2): 71–9. PMID 7511544.CS1 maint: Multiple names: authors list (link)
• Kato M, Ishizaki A, Hellman U; et al. (1995). "A human keratinocyte cell line produces two autocrine growth inhibitors, transforming growth factor-beta and insulin-like growth factor binding protein-6, in a calcium- and cell density-dependent manner". J. Biol. Chem. 270 (21): 12373–9. PMID 7539002.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Delhanty PJ, Hill DJ, Shimasaki S, Han VK (1993). "Insulin-like growth factor binding protein-4, -5 and -6 mRNAs in the human fetus: localization to sites of growth and differentiation?". Growth Regul. 3 (1): 8–11. PMID 7683540.CS1 maint: Multiple names: authors list (link)
• Bach LA, Hsieh S, Sakano K; et al. (1993). "Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6". J. Biol. Chem. 268 (13): 9246–54. PMID 7683646.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wegmann BR, Schöneberger HJ, Kiefer PE; et al. (1993). "Molecular cloning of IGFBP-5 from SCLC cell lines and expression of IGFBP-4, IGFBP-5 and IGFBP-6 in lung cancer cell lines and primary tumours". Eur. J. Cancer. 29A (11): 1578–84. PMID 7692907.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Neumann GM, Marinaro JA, Bach LA (1998). "Identification of O-glycosylation sites and partial characterization of carbohydrate structure and disulfide linkages of human insulin-like growth factor binding protein 6". Biochemistry. 37 (18): 6572–85. doi:10.1021/bi972894e. PMID 9572875.CS1 maint: Multiple names: authors list (link)
• Ehrenborg E, Zazzi H, Lagercrantz S; et al. (1999). "Characterization and chromosomal localization of the human insulin-like growth factor-binding protein 6 gene". Mamm. Genome. 10 (4): 376–80. PMID 10087296.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Neumann GM, Bach LA (1999). "The N-terminal disulfide linkages of human insulin-like growth factor-binding protein-6 (hIGFBP-6) and hIGFBP-1 are different as determined by mass spectrometry". J. Biol. Chem. 274 (21): 14587–94. PMID 10329650.
• Wong MS, Fong CC, Yang M (1999). "Biosensor measurement of the interaction kinetics between insulin-like growth factors and their binding proteins". Biochim. Biophys. Acta. 1432 (2): 293–301. PMID 10407151.CS1 maint: Multiple names: authors list (link)
• Yu H, Mistry J, Nicar MJ; et al. (1999). "Insulin-like growth factors (IGF-I, free IGF-I and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, IGFBP-3, IGFBP-6, and ALS) in blood circulation". J. Clin. Lab. Anal. 13 (4): 166–72. PMID 10414596.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dailly YP, Zhou Y, Linkhart TA; et al. (2001). "Structure and characterization of the human insulin-like growth factor binding protein (IGFBP)-6 promoter: identification of a functional retinoid response element". Biochim. Biophys. Acta. 1518 (1–2): 145–51. PMID 11267670.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weinzimer SA, Gibson TB, Collett-Solberg PF; et al. (2001). "Transferrin is an insulin-like growth factor-binding protein-3 binding protein". J. Clin. Endocrinol. Metab. 86 (4): 1806–13. PMID 11297622.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)