KLK2

Kallikrein-related peptidase 2
Identifiers
Symbols	KLK2 ; KLK2A2; MGC12201; hK2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 68141
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE KLK2 209854 s at tn.png
File:PBB GE KLK2 209855 s at tn.png
File:PBB GE KLK2 210339 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Kallikrein-related peptidase 2, also known as KLK2, is a human gene.

Further reading

• Riegman PH, Vlietstra RJ, van der Korput HA; et al. (1992). "Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species". Mol. Cell. Endocrinol. 76 (1–3): 181–90. PMID 1726490.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Qin H, Kemp J, Yip MY; et al. (1992). "Localization of human glandular kallikrein-1 gene to chromosome 19q13.3-13.4 by in situ hybridization". Hum. Hered. 41 (4): 222–6. PMID 1783409.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Riegman PH, Vlietstra RJ, Klaassen P; et al. (1989). "The prostate-specific antigen gene and the human glandular kallikrein-1 gene are tandemly located on chromosome 19". FEBS Lett. 247 (1): 123–6. PMID 2468530.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Schedlich LJ, Bennetts BH, Morris BJ (1988). "Primary structure of a human glandular kallikrein gene". DNA. 6 (5): 429–37. PMID 2824146.CS1 maint: Multiple names: authors list (link)
• Frenette G, Deperthes D, Tremblay RR; et al. (1997). "Purification of enzymatically active kallikrein hK2 from human seminal plasma". Biochim. Biophys. Acta. 1334 (1): 109–15. PMID 9042371.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bourgeois L, Brillard-Bourdet M, Deperthes D; et al. (1997). "Serpin-derived peptide substrates for investigating the substrate specificity of human tissue kallikreins hK1 and hK2". J. Biol. Chem. 272 (47): 29590–5. PMID 9368023.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mikolajczyk SD, Millar LS, Kumar A, Saedi MS (1998). "Human glandular kallikrein, hK2, shows arginine-restricted specificity and forms complexes with plasma protease inhibitors". Prostate. 34 (1): 44–50. PMID 9428387.CS1 maint: Multiple names: authors list (link)
• Yu DC, Sakamoto GT, Henderson DR (1999). "Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy". Cancer Res. 59 (7): 1498–504. PMID 10197620.CS1 maint: Multiple names: authors list (link)
• Mikolajczyk SD, Millar LS, Kumar A, Saedi MS (1999). "Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1". Int. J. Cancer. 81 (3): 438–42. PMID 10209959.CS1 maint: Multiple names: authors list (link)
• Lövgren J, Valtonen-André C, Marsal K; et al. (1999). "Measurement of prostate-specific antigen and human glandular kallikrein 2 in different body fluids". J. Androl. 20 (3): 348–55. PMID 10386814.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cargill M, Altshuler D, Ireland J; et al. (1999). "Characterization of single-nucleotide polymorphisms in coding regions of human genes". Nat. Genet. 22 (3): 231–8. doi:10.1038/10290. PMID 10391209.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lövgren J, Airas K, Lilja H (1999). "Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors". Eur. J. Biochem. 262 (3): 781–9. PMID 10411640.CS1 maint: Multiple names: authors list (link)
• Mikolajczyk SD, Millar LS, Marker KM; et al. (1999). "Identification of a novel complex between human kallikrein 2 and protease inhibitor-6 in prostate cancer tissue". Cancer Res. 59 (16): 3927–30. PMID 10463585.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu XF, Essand M, Vasmatzis G; et al. (1999). "Identification of three new alternate human kallikrein 2 transcripts: evidence of long transcript and alternative splicing". Biochem. Biophys. Res. Commun. 264 (3): 833–9. doi:10.1006/bbrc.1999.1595. PMID 10544017.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ren F, Zhang S, Mitchell SH; et al. (2000). "Tea polyphenols down-regulate the expression of the androgen receptor in LNCaP prostate cancer cells". Oncogene. 19 (15): 1924–32. doi:10.1038/sj.onc.1203511. PMID 10773882.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Harvey TJ, Hooper JD, Myers SA; et al. (2001). "Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4". J. Biol. Chem. 275 (48): 37397–406. doi:10.1074/jbc.M004525200. PMID 10969073.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen VC, Chao L, Chao J (2001). "A positively charged loop on the surface of kallistatin functions to enhance tissue kallikrein inhibition by acting as a secondary binding site for kallikrein". J. Biol. Chem. 275 (51): 40371–7. doi:10.1074/jbc.M005691200. PMID 10991942.CS1 maint: Multiple names: authors list (link)
• Gan L, Lee I, Smith R; et al. (2001). "Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region". Gene. 257 (1): 119–30. PMID 11054574.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Réhault S, Monget P, Mazerbourg S; et al. (2001). "Insulin-like growth factor binding proteins (IGFBPs) as potential physiological substrates for human kallikreins hK2 and hK3". Eur. J. Biochem. 268 (10): 2960–8. PMID 11358513.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Saedi MS, Zhu Z, Marker K; et al. (2002). "Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells". Int. J. Cancer. 94 (4): 558–63. PMID 11745444.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)