LRP5

Low density lipoprotein receptor-related protein 5
Identifiers
Symbols	LRP5 ; HBM; BMND1; EVR1; EVR4; LR3; LRP7; OPPG; OPS; OPTA1; VBCH2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 1746
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE LRP5 209468 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Low density lipoprotein receptor-related protein 5, also known as LRP5, is a human gene.

Further reading

• He X, Semenov M, Tamai K, Zeng X (2004). "LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way". Development. 131 (8): 1663–77. doi:10.1242/dev.01117. PMID 15084453.CS1 maint: Multiple names: authors list (link)
• Godyna S, Liau G, Popa I; et al. (1995). "Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1". J. Cell Biol. 129 (5): 1403–10. PMID 7775583.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gong Y, Vikkula M, Boon L; et al. (1996). "Osteoporosis-pseudoglioma syndrome, a disorder affecting skeletal strength and vision, is assigned to chromosome region 11q12-13". Am. J. Hum. Genet. 59 (1): 146–51. PMID 8659519.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Johnson ML, Gong G, Kimberling W; et al. (1997). "Linkage of a gene causing high bone mass to human chromosome 11 (11q12-13)". Am. J. Hum. Genet. 60 (6): 1326–32. PMID 9199553.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hey PJ, Twells RC, Phillips MS; et al. (1998). "Cloning of a novel member of the low-density lipoprotein receptor family". Gene. 216 (1): 103–11. PMID 9714764.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dong Y, Lathrop W, Weaver D; et al. (1998). "Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity". Biochem. Biophys. Res. Commun. 251 (3): 784–90. doi:10.1006/bbrc.1998.9545. PMID 9790987.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• de Crecchio G, Simonelli F, Nunziata G; et al. (1999). "Autosomal recessive familial exudative vitreoretinopathy: evidence for genetic heterogeneity". Clin. Genet. 54 (4): 315–20. PMID 9831343.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen D, Lathrop W, Dong Y (1999). "Molecular cloning of mouse Lrp7(Lr3) cDNA and chromosomal mapping of orthologous genes in mouse and human". Genomics. 55 (3): 314–21. doi:10.1006/geno.1998.5688. PMID 10049586.CS1 maint: Multiple names: authors list (link)
• Mao J, Wang J, Liu B; et al. (2001). "Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway". Mol. Cell. 7 (4): 801–9. PMID 11336703.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Twells RC, Metzker ML, Brown SD; et al. (2001). "The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13". Genomics. 72 (3): 231–42. doi:10.1006/geno.2000.6492. PMID 11401438.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Semënov MV, Tamai K, Brott BK; et al. (2001). "Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6". Curr. Biol. 11 (12): 951–61. PMID 11448771.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zorn AM (2001). "Wnt signalling: antagonistic Dickkopfs". Curr. Biol. 11 (15): R592–5. PMID 11516963.
• Gong Y, Slee RB, Fukai N; et al. (2002). "LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development". Cell. 107 (4): 513–23. PMID 11719191.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Little RD, Carulli JP, Del Mastro RG; et al. (2002). "A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait". Am. J. Hum. Genet. 70 (1): 11–9. PMID 11741193.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Okubo M, Horinishi A, Kim DH; et al. (2002). "Seven novel sequence variants in the human low density lipoprotein receptor related protein 5 (LRP5) gene". Hum. Mutat. 19 (2): 186. doi:10.1002/humu.9012. PMID 11793484.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Boyden LM, Mao J, Belsky J; et al. (2002). "High bone density due to a mutation in LDL-receptor-related protein 5". N. Engl. J. Med. 346 (20): 1513–21. doi:10.1056/NEJMoa013444. PMID 12015390.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Van Hul E, Gram J, Bollerslev J; et al. (2002). "Localization of the gene causing autosomal dominant osteopetrosis type I to chromosome 11q12-13". J. Bone Miner. Res. 17 (6): 1111–7. PMID 12054167.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fujino T, Asaba H, Kang MJ; et al. (2003). "Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion". Proc. Natl. Acad. Sci. U.S.A. 100 (1): 229–34. doi:10.1073/pnas.0133792100. PMID 12509515.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Van Wesenbeeck L, Cleiren E, Gram J; et al. (2003). "Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density". Am. J. Hum. Genet. 72 (3): 763–71. PMID 12579474.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)