Lipotropin

proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)
Identifiers
Symbol	POMC
Entrez	5443
HUGO	9201
OMIM	176830
RefSeq	NM_000939
UniProt	P01189
Other data
Locus	Chr. 2 p23

WikiDoc Resources for Lipotropin
Articles
Most recent articles on Lipotropin Most cited articles on Lipotropin Review articles on Lipotropin Articles on Lipotropin in N Eng J Med, Lancet, BMJ
Media
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Evidence Based Medicine
Cochrane Collaboration on Lipotropin Bandolier on Lipotropin TRIP on Lipotropin
Clinical Trials
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Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Lipotropin NICE Guidance on Lipotropin NHS PRODIGY Guidance FDA on Lipotropin CDC on Lipotropin
Books
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News
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Commentary
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Definitions
Definitions of Lipotropin
Patient Resources / Community
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Healthcare Provider Resources
Symptoms of Lipotropin Causes & Risk Factors for Lipotropin Diagnostic studies for Lipotropin Treatment of Lipotropin
Continuing Medical Education (CME)
CME Programs on Lipotropin
International
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Business
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Experimental / Informatics
List of terms related to Lipotropin

Lipotropin is a hormone produced by the cleavage of pro-opiomelanocortin (POMC). The anterior pituitary gland produces the pro-hormone POMC, which undergoes cleavage to adrenocorticotropin (ACTH) and β-lipotropin (β-LPH).

Beta-lipotropin

β-lipotropin is a 90 amino acid polypeptide that stimulates melanocytes to produce melanin, and can also be cleaved into smaller peptides. In humans, γ-lipotropin, α-MSH, β-MSH, γ-MSH, α-endorphin, β-endorphin, γ-endorphin, and met-enkephalin are all possible fragments of β-lipotropin.

β-lipotropin is the carboxy-terminal fragment of POMC, and performs lipid-mobilizing functions such as lipolysis and steroidogenesis.

Gamma-lipotropin

γ-lipotropin is the amino-terminal peptide fragment of β-lipotropin. In humans, it has 56 amino acids.

External links

• beta-Lipotropin at the US National Library of Medicine Medical Subject Headings (MeSH)
• gamma-Lipotropin at the US National Library of Medicine Medical Subject Headings (MeSH)