MLLT10

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Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
Identifiers
Symbols MLLT10 ; AF10; DKFZp686E10210; MGC75086
External IDs Template:OMIM5 Template:MGI HomoloGene20973
RNA expression pattern
File:PBB GE MLLT10 216503 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10, also known as MLLT10, is a human gene.[1]


References

  1. "Entrez Gene: MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10".

Further reading

  • Chaplin T, Ayton P, Bernard OA; et al. (1995). "A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia". Blood. 85 (6): 1435–41. PMID 7888665.
  • Silliman CC, McGavran L, Wei Q; et al. (1998). "Alternative splicing in wild-type AF10 and CALM cDNAs and in AF10-CALM and CALM-AF10 fusion cDNAs produced by the t(10;11)(p13-14;q14-q21) suggests a potential role for truncated AF10 polypeptides". Leukemia. 12 (9): 1404–10. PMID 9737689.
  • Linder B, Newman R, Jones LK; et al. (2000). "Biochemical analyses of the AF10 protein: the extended LAP/PHD-finger mediates oligomerisation". J. Mol. Biol. 299 (2): 369–78. doi:10.1006/jmbi.2000.3766. PMID 10860745.
  • Lillington DM, Jaju RJ, Shankar AG; et al. (2000). "Cytogenetic and molecular evidence of marrow involvement in extramedullary acute myeloid leukaemia". Br. J. Haematol. 110 (3): 547–51. PMID 10997963.
  • de Bruijn DR, dos Santos NR, Thijssen J; et al. (2001). "The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10". Oncogene. 20 (25): 3281–9. doi:10.1038/sj.onc.1204419. PMID 11423977.
  • Debernardi S, Bassini A, Jones LK; et al. (2002). "The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex". Blood. 99 (1): 275–81. PMID 11756182.
  • Cai Y, Gao Y, Sheng Q; et al. (2002). "Characterization and potential function of a novel testis-specific nucleoporin BS-63". Mol. Reprod. Dev. 61 (1): 126–34. doi:10.1002/mrd.1139. PMID 11774384.
  • Roll P, Zattara-Cannoni H, Bustos-Bernard MC; et al. (2002). "Molecular and fluorescence in situ hybridization analysis of a 10;11 rearrangement in a case of infant acute monocytic leukemia". Cancer Genet. Cytogenet. 135 (2): 187–91. PMID 12127405.
  • Nakamura T, Mori T, Tada S; et al. (2003). "ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation". Mol. Cell. 10 (5): 1119–28. PMID 12453419.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Perrin L, Bloyer S, Ferraz C; et al. (2003). "The leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusions". Mol. Cell. Biol. 23 (1): 119–30. PMID 12482966.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Deloukas P, Earthrowl ME, Grafham DV; et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
  • Okada Y, Feng Q, Lin Y; et al. (2005). "hDOT1L links histone methylation to leukemogenesis". Cell. 121 (2): 167–78. doi:10.1016/j.cell.2005.02.020. PMID 15851025.

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