Metallothionein 1A

Metallothionein 1A
File:PBB Protein MT1A image.jpg PDB rendering based on 1mhu.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1mhu​, 1mrb​, 2mhu​
Identifiers
Symbols	MT1A ; MGC32848; MT1; MT1S; MTC
External IDs	Template:OMIM5 HomoloGene: 88733
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Metallothionein 1A, also known as MT1A, is a human gene.

Further reading

• Thirumoorthy N, Manisenthil Kumar KT, Shyam Sundar A; et al. (2007). "Metallothionein: an overview". World J. Gastroenterol. 13 (7): 993–6. PMID 17373731.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sutherland GR, Baker E, Callen DF; et al. (1990). "The human metallothionein gene cluster is not disrupted in myelomonocytic leukemia". Genomics. 6 (1): 144–8. PMID 2303255.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Grider A, Bailey LB, Cousins RJ (1990). "Erythrocyte metallothionein as an index of zinc status in humans". Proc. Natl. Acad. Sci. U.S.A. 87 (4): 1259–62. PMID 2304897.CS1 maint: Multiple names: authors list (link)
• Le Beau MM, Diaz MO, Karin M, Rowley JD (1985). "Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia". Nature. 313 (6004): 709–11. PMID 3856101.CS1 maint: Multiple names: authors list (link)
• Hunziker PE, Kägi JH (1985). "Isolation and characterization of six human hepatic isometallothioneins". Biochem. J. 231 (2): 375–82. PMID 4062903.
• Karin M, Eddy RL, Henry WM; et al. (1984). "Human metallothionein genes are clustered on chromosome 16". Proc. Natl. Acad. Sci. U.S.A. 81 (17): 5494–8. PMID 6089206.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Richards RI, Heguy A, Karin M (1984). "Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids". Cell. 37 (1): 263–72. PMID 6327055.CS1 maint: Multiple names: authors list (link)
• Armitage IM, Otvos JD, Briggs RW, Boulanger Y (1983). "Structure elucidation of the metal-binding sites in metallothionein by 113Cd NMR". Fed. Proc. 41 (13): 2974–80. PMID 7140998.CS1 maint: Multiple names: authors list (link)
• Akintola DF, Sampson B, Fleck A (1995). "Development of an enzyme-linked immunosorbent assay for human metallothionein-1 in plasma and urine". J. Lab. Clin. Med. 126 (2): 119–27. PMID 7543551.CS1 maint: Multiple names: authors list (link)
• Davis SR, McMahon RJ, Cousins RJ (1998). "Metallothionein knockout and transgenic mice exhibit altered intestinal processing of zinc with uniform zinc-dependent zinc transporter-1 expression". J. Nutr. 128 (5): 825–31. PMID 9566988.CS1 maint: Multiple names: authors list (link)
• Simpkins C, Lloyd T, Li S, Balderman S (1998). "Metallothionein-induced increase in mitochondrial inner membrane permeability". J. Surg. Res. 75 (1): 30–4. doi:10.1006/jsre.1997.5241. PMID 9614853.CS1 maint: Multiple names: authors list (link)
• Lau JC, Cherian MG (1999). "Developmental changes in hepatic metallothionein, zinc, and copper levels in genetically altered mice". Biochem. Cell Biol. 76 (4): 615–23. PMID 10099782.
• Levadoux M, Mahon C, Beattie JH; et al. (2000). "Nuclear import of metallothionein requires its mRNA to be associated with the perinuclear cytoskeleton". J. Biol. Chem. 274 (49): 34961–6. PMID 10574972.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Garrett SH, Sens MA, Shukla D; et al. (2000). "Metallothionein isoform 1 and 2 gene expression in the human prostate: downregulation of MT-1X in advanced prostate cancer". Prostate. 43 (2): 125–35. PMID 10754528.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vandeghinste N, Proost P, De Ley M (2000). "Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes". Cell. Mol. Biol. (Noisy-le-grand). 46 (2): 419–33. PMID 10774930.CS1 maint: Multiple names: authors list (link)
• Campagne MV, Thibodeaux H, van Bruggen N; et al. (2000). "Increased binding activity at an antioxidant-responsive element in the metallothionein-1 promoter and rapid induction of metallothionein-1 and -2 in response to cerebral ischemia and reperfusion". J. Neurosci. 20 (14): 5200–7. PMID 10884303.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rahman MT, De Ley M (2001). "Metallothionein isogene transcription in red blood cell precursors from human cord blood". Eur. J. Biochem. 268 (3): 849–56. PMID 11168427.
• Levadoux-Martin M, Hesketh JE, Beattie JH, Wallace HM (2001). "Influence of metallothionein-1 localization on its function". Biochem. J. 355 (Pt 2): 473–9. PMID 11284736.CS1 maint: Multiple names: authors list (link)
• Richarz AN, Brätter P (2002). "Speciation analysis of trace elements in the brains of individuals with Alzheimer's disease with special emphasis on metallothioneins". Analytical and bioanalytical chemistry. 372 (3): 412–7. doi:10.1007/s00216-001-1187-5. PMID 11939525.
• Minami T, Kubo K, Ichida S (2003). "Determination of metallothionein-1/metallothionein-2 ratios in the mouse liver and pancreas by capillary zone electrophoresis using a polyacrylamide-coated capillary at neutral pH". J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 779 (2): 211–9. PMID 12361735.CS1 maint: Multiple names: authors list (link)