Metallothionein 2A

Metallothionein 2A
File:PBB Protein MT2A image.jpg PDB rendering based on 1mhu.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1mhu​, 1mrb​, 1mrt​, 2mhu​
Identifiers
Symbols	MT2A ; MT2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 48388
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE MT2A 212185 x at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Metallothionein 2A, also known as MT2A, is a human gene.

Further reading

• Kissling MM, Kägi HR (1977). "Primary structure of human hepatic metallothionein". FEBS Lett. 82 (2): 247–50. PMID 913597.
• Yamazaki S, Nakanishi M, Hamamoto T; et al. (1993). "Expression of human metallothionein-II fusion protein in Escherichia coli". Biochem. Int. 28 (3): 451–60. PMID 1339282.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Messerle BA, Schäffer A, Vasák M; et al. (1992). "Comparison of the solution conformations of human [Zn7]-metallothionein-2 and [Cd7]-metallothionein-2 using nuclear magnetic resonance spectroscopy". J. Mol. Biol. 225 (2): 433–43. PMID 1593628.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zafarullah M, Martel-Pelletier J, Cloutier JM; et al. (1992). "Expression of c-fos, c-jun, jun-B, metallothionein and metalloproteinase genes in human chondrocyte". FEBS Lett. 306 (2–3): 169–72. PMID 1633872.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Messerle BA, Schäffer A, Vasák M; et al. (1990). "Three-dimensional structure of human [113Cd7]metallothionein-2 in solution determined by nuclear magnetic resonance spectroscopy". J. Mol. Biol. 214 (3): 765–79. PMID 2388267.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Duguid JR, Bohmont CW, Liu NG, Tourtellotte WW (1989). "Changes in brain gene expression shared by scrapie and Alzheimer disease". Proc. Natl. Acad. Sci. U.S.A. 86 (18): 7260–4. PMID 2780570.CS1 maint: Multiple names: authors list (link)
• Karin M, Haslinger A, Heguy A; et al. (1987). "Metal-responsive elements act as positive modulators of human metallothionein-IIA enhancer activity". Mol. Cell. Biol. 7 (2): 606–13. PMID 3821726.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Karin M, Haslinger A, Holtgreve H; et al. (1984). "Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene". Nature. 308 (5959): 513–9. PMID 6323998.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Schmidt CJ, Hamer DH, McBride OW (1984). "Chromosomal location of human metallothionein genes: implications for Menkes' disease". Science. 224 (4653): 1104–6. PMID 6719135.CS1 maint: Multiple names: authors list (link)
• Karin M, Richards RI (1982). "Human metallothionein genes: molecular cloning and sequence analysis of the mRNA". Nucleic Acids Res. 10 (10): 3165–73. PMID 6896577.
• Karin M, Richards RI (1982). "Human metallothionein genes--primary structure of the metallothionein-II gene and a related processed gene". Nature. 299 (5886): 797–802. PMID 7133118.
• Lambert E, Kille P, Swaminathan R (1996). "Cloning and sequencing a novel metallothionein I isoform expressed in human reticulocytes". FEBS Lett. 389 (2): 210–2. PMID 8766831.CS1 maint: Multiple names: authors list (link)
• Woo ES, Dellapiazza D, Wang AS, Lazo JS (1999). "Energy-dependent nuclear binding dictates metallothionein localization". J. Cell. Physiol. 182 (1): 69–76. doi:10.1002/(SICI)1097-4652(200001)182:1<69::AID-JCP8>3.0.CO;2-9. PMID 10567918.CS1 maint: Multiple names: authors list (link)
• Jiang LJ, Vasák M, Vallee BL, Maret W (2000). "Zinc transfer potentials of the alpha - and beta-clusters of metallothionein are affected by domain interactions in the whole molecule". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2503–8. PMID 10716985.CS1 maint: Multiple names: authors list (link)
• Garrett SH, Sens MA, Shukla D; et al. (2000). "Metallothionein isoform 1 and 2 gene expression in the human prostate: downregulation of MT-1X in advanced prostate cancer". Prostate. 43 (2): 125–35. PMID 10754528.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ebert MP, Günther T, Hoffmann J; et al. (2000). "Expression of metallothionein II in intestinal metaplasia, dysplasia, and gastric cancer". Cancer Res. 60 (7): 1995–2001. PMID 10766190.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Toyama M, Yamashita M, Hirayama N, Murooka Y (2003). "Interactions of arsenic with human metallothionein-2". J. Biochem. 132 (2): 217–21. PMID 12153718.CS1 maint: Multiple names: authors list (link)
• Sun X, Kang YJ (2002). "Prior increase in metallothionein levels is required to prevent doxorubicin cardiotoxicity". Exp. Biol. Med. (Maywood). 227 (8): 652–7. PMID 12192109.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Izmailova E, Bertley FM, Huang Q; et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages". Nat. Med. 9 (2): 191–7. doi:10.1038/nm822. PMID 12539042.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)