NEDD9

Neural precursor cell expressed, developmentally down-regulated 9
Identifiers
Symbols	NEDD9 ; CAS-L; CASL; HEF1; dJ49G10.2; dJ761I2.1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4669
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE NEDD9 202149 at tn.png
File:PBB GE NEDD9 202150 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Neural precursor cell expressed, developmentally down-regulated 9, also known as NEDD9, is a human gene.

Further reading

• Iwata S, Ohashi Y, Kamiguchi K, Morimoto C (2000). "Beta 1-integrin-mediated cell signaling in T lymphocytes". J. Dermatol. Sci. 23 (2): 75–86. PMID 10808124.CS1 maint: Multiple names: authors list (link)
• O'Neill GM, Seo S, Serebriiskii IG; et al. (2007). "A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9". Cancer Res. 67 (19): 8975–9. doi:10.1158/0008-5472.CAN-07-1328. PMID 17908996.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Law SF, Estojak J, Wang B; et al. (1996). "Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae". Mol. Cell. Biol. 16 (7): 3327–37. PMID 8668148.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Minegishi M, Tachibana K, Sato T; et al. (1996). "Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes". J. Exp. Med. 184 (4): 1365–75. PMID 8879209.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Manié SN, Beck AR, Astier A; et al. (1997). "Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells". J. Biol. Chem. 272 (7): 4230–6. PMID 9020138.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tachibana K, Urano T, Fujita H; et al. (1997). "Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates". J. Biol. Chem. 272 (46): 29083–90. PMID 9360983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hunter AJ, Shimizu Y (1997). "Alpha 4 beta 1 integrin-mediated tyrosine phosphorylation in human T cells: characterization of Crk- and Fyn-associated substrates (pp105, pp115, and human enhancer of filamentation-1) and integrin-dependent activation of p59fyn1". J. Immunol. 159 (10): 4806–14. PMID 9366405.
• de Jong R, van Wijk A, Haataja L; et al. (1998). "BCR/ABL-induced leukemogenesis causes phosphorylation of Hef1 and its association with Crkl". J. Biol. Chem. 272 (51): 32649–55. PMID 9405482.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ohashi Y, Tachibana K, Kamiguchi K; et al. (1998). "T cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3G". J. Biol. Chem. 273 (11): 6446–51. PMID 9497377.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Astier A, Manié SN, Law SF; et al. (1998). "Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells". Leuk. Lymphoma. 28 (1–2): 65–72. PMID 9498705.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Law SF, Zhang YZ, Klein-Szanto AJ, Golemis EA (1998). "Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments". Mol. Cell. Biol. 18 (6): 3540–51. PMID 9584194.CS1 maint: Multiple names: authors list (link)
• Côté JF, Charest A, Wagner J, Tremblay ML (1998). "Combination of gene targeting and substrate trapping to identify substrates of protein tyrosine phosphatases using PTP-PEST as a model". Biochemistry. 37 (38): 13128–37. doi:10.1021/bi981259l. PMID 9748319.CS1 maint: Multiple names: authors list (link)
• Kyono WT, de Jong R, Park RK; et al. (1998). "Differential interaction of Crkl with Cbl or C3G, Hef-1, and gamma subunit immunoreceptor tyrosine-based activation motif in signaling of myeloid high affinity Fc receptor for IgG (Fc gamma RI)". J. Immunol. 161 (10): 5555–63. PMID 9820532.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang Z, Hernandez-Lagunas L, Horne WC, Baron R (1999). "Cytoskeleton-dependent tyrosine phosphorylation of the p130(Cas) family member HEF1 downstream of the G protein-coupled calcitonin receptor. Calcitonin induces the association of HEF1, paxillin, and focal adhesion kinase". J. Biol. Chem. 274 (35): 25093–8. PMID 10455189.CS1 maint: Multiple names: authors list (link)
• Ohashi Y, Iwata S, Kamiguchi K, Morimoto C (1999). "Tyrosine phosphorylation of Crk-associated substrate lymphocyte-type is a critical element in TCR- and beta 1 integrin-induced T lymphocyte migration". J. Immunol. 163 (7): 3727–34. PMID 10490968.CS1 maint: Multiple names: authors list (link)
• Law SF, Zhang YZ, Fashena SJ; et al. (1999). "Dimerization of the docking/adaptor protein HEF1 via a carboxy-terminal helix-loop-helix domain". Exp. Cell Res. 252 (1): 224–35. doi:10.1006/excr.1999.4609. PMID 10502414.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Scanlan MJ, Gordan JD, Williamson B; et al. (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma". Int. J. Cancer. 83 (4): 456–64. PMID 10508479.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sakakibara A, Hattori S (2000). "Chat, a Cas/HEF1-associated adaptor protein that integrates multiple signaling pathways". J. Biol. Chem. 275 (9): 6404–10. PMID 10692442.
• Law SF, O'Neill GM, Fashena SJ; et al. (2000). "The docking protein HEF1 is an apoptotic mediator at focal adhesion sites". Mol. Cell. Biol. 20 (14): 5184–95. PMID 10866674.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)