NOV (gene)

Nephroblastoma overexpressed gene
Identifiers
Symbols	NOV ; CCN3; IGFBP9; NOVH
External IDs	Template:OMIM5 Template:MGI HomoloGene: 1884
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE NOV 214321 at tn.png
File:PBB GE NOV 204501 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Nephroblastoma overexpressed gene, also known as NOV, is a human gene.

Further reading

• Perbal B (2007). "The CCN3 protein and cancer". Adv. Exp. Med. Biol. 587: 23–40. PMID 17163153.
• Martinerie C, Viegas-Pequignot E, Guenard I; et al. (1993). "Physical mapping of human loci homologous to the chicken nov proto-oncogene". Oncogene. 7 (12): 2529–34. PMID 1334251.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Martinerie C, Huff V, Joubert I; et al. (1994). "Structural analysis of the human nov proto-oncogene and expression in Wilms tumor". Oncogene. 9 (9): 2729–32. PMID 7520150.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Martinerie C, Chevalier G, Rauscher FJ, Perbal B (1996). "Regulation of nov by WT1: a potential role for nov in nephrogenesis". Oncogene. 12 (7): 1479–92. PMID 8622864.CS1 maint: Multiple names: authors list (link)
• Perbal B, Martinerie C, Sainson R; et al. (1999). "The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling". Proc. Natl. Acad. Sci. U.S.A. 96 (3): 869–74. PMID 9927660.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Burren CP, Wilson EM, Hwa V; et al. (1999). "Binding properties and distribution of insulin-like growth factor binding protein-related protein 3 (IGFBP-rP3/NovH), an additional member of the IGFBP Superfamily". J. Clin. Endocrinol. Metab. 84 (3): 1096–103. PMID 10084601.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Perbal B (1999). "Nuclear localisation of NOVH protein: a potential role for NOV in the regulation of gene expression". MP, Mol. Pathol. 52 (2): 84–91. PMID 10474687.
• Albrecht C, von Der Kammer H, Mayhaus M; et al. (2000). "Muscarinic acetylcholine receptors induce the expression of the immediate early growth regulatory gene CYR61". J. Biol. Chem. 275 (37): 28929–36. doi:10.1074/jbc.M003053200. PMID 10852911.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Martinerie C, Gicquel C, Louvel A; et al. (2001). "Altered expression of novH is associated with human adrenocortical tumorigenesis". J. Clin. Endocrinol. Metab. 86 (8): 3929–40. PMID 11502835.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Manara MC, Perbal B, Benini S; et al. (2002). "The expression of ccn3(nov) gene in musculoskeletal tumors". Am. J. Pathol. 160 (3): 849–59. PMID 11891184.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sakamoto K, Yamaguchi S, Ando R; et al. (2002). "The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway". J. Biol. Chem. 277 (33): 29399–405. doi:10.1074/jbc.M203727200. PMID 12050162.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Li CL, Martinez V, He B; et al. (2002). "A role for CCN3 (NOV) in calcium signalling". MP, Mol. Pathol. 55 (4): 250–61. PMID 12147716.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Thibout H, Martinerie C, Créminon C; et al. (2003). "Characterization of human NOV in biological fluids: an enzyme immunoassay for the quantification of human NOV in sera from patients with diseases of the adrenal gland and of the nervous system". J. Clin. Endocrinol. Metab. 88 (1): 327–36. PMID 12519873.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lin CG, Leu SJ, Chen N; et al. (2003). "CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family". J. Biol. Chem. 278 (26): 24200–8. doi:10.1074/jbc.M302028200. PMID 12695522.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ellis PD, Metcalfe JC, Hyvönen M, Kemp PR (2003). "Adhesion of endothelial cells to NOV is mediated by the integrins alphavbeta3 and alpha5beta1". J. Vasc. Res. 40 (3): 234–43. doi:10.1159/000071887. PMID 12902636.CS1 maint: Multiple names: authors list (link)
• Laurent M, Martinerie C, Thibout H; et al. (2003). "NOVH increases MMP3 expression and cell migration in glioblastoma cells via a PDGFR-alpha-dependent mechanism". FASEB J. 17 (13): 1919–21. doi:10.1096/fj.02-1023fje. PMID 14519668.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lombet A, Planque N, Bleau AM; et al. "CCN3 and calcium signaling". 1 (1): 1. doi:10.1186/1478-811X-1-1. PMID 14606958.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Schild C, Trueb B (2004). "Three members of the connective tissue growth factor family CCN are differentially regulated by mechanical stress". Biochim. Biophys. Acta. 1691 (1): 33–40. doi:10.1016/j.bbamcr.2003.12.001. PMID 15053922.
• Gellhaus A, Dong X, Propson S; et al. (2004). "Connexin43 interacts with NOV: a possible mechanism for negative regulation of cell growth in choriocarcinoma cells". J. Biol. Chem. 279 (35): 36931–42. doi:10.1074/jbc.M404073200. PMID 15181016.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)