NUPR1
| Nuclear protein 1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | NUPR1 ; P8; COM1 | ||||||||||
| External IDs | Template:MGI HomoloGene: 8229 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE NUPR1 209230 s at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Nuclear protein 1, also known as NUPR1, is a human gene.[1]
References
Further reading
- Mallo GV, Fiedler F, Calvo EL; et al. (1998). "Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth". J. Biol. Chem. 272 (51): 32360–9. PMID 9405444.
- Vasseur S, Vidal Mallo G, Fiedler F; et al. (1999). "Cloning and expression of the human p8, a nuclear protein with mitogenic activity". Eur. J. Biochem. 259 (3): 670–5. PMID 10092851.
- Ree AH, Tvermyr M, Engebraaten O; et al. (1999). "Expression of a novel factor in human breast cancer cells with metastatic potential". Cancer Res. 59 (18): 4675–80. PMID 10493524.
- Loftus BJ, Kim UJ, Sneddon VP; et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
- Hoffmeister A, Ropolo A, Vasseur S; et al. (2002). "The HMG-I/Y-related protein p8 binds to p300 and Pax2 trans-activation domain-interacting protein to regulate the trans-activation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter". J. Biol. Chem. 277 (25): 22314–9. doi:10.1074/jbc.M201657200. PMID 11940591.
- Ree AH, Bratland A, Kroes RA; et al. (2002). "Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases". Anticancer Res. 22 (4): 1949–57. PMID 12174869.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Suzuki Y, Yamashita R, Shirota M; et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Jiang WG, Davies G, Fodstad O (2005). "Com-1/P8 in oestrogen regulated growth of breast cancer cells, the ER-beta connection". Biochem. Biophys. Res. Commun. 330 (1): 253–62. doi:10.1016/j.bbrc.2005.02.157. PMID 15781258.
- Mao Y, Zhao Y, Zhou LF; et al. (2006). "A novel gene mutation (1292 deletion) in a Chinese family with cerebral cavernous malformations". Neurosurgery. 56 (5): 1149–53, discussion 1149-53. PMID 15854263.
- Ito Y, Yoshida H, Motoo Y; et al. (2005). "Expression of p8 protein in medullary thyroid carcinoma". Anticancer Res. 25 (5): 3419–23. PMID 16101158.
- Valacco MP, Varone C, Malicet C; et al. (2006). "Cell growth-dependent subcellular localization of p8". J. Cell. Biochem. 97 (5): 1066–79. doi:10.1002/jcb.20682. PMID 16294328.
- Malicet C, Hoffmeister A, Moreno S; et al. (2006). "Interaction of the stress protein p8 with Jab1 is required for Jab1-dependent p27 nuclear-to-cytoplasm translocation". Biochem. Biophys. Res. Commun. 339 (1): 284–9. doi:10.1016/j.bbrc.2005.11.018. PMID 16300740.
- Malicet C, Giroux V, Vasseur S; et al. (2006). "Regulation of apoptosis by the p8/prothymosin alpha complex". Proc. Natl. Acad. Sci. U.S.A. 103 (8): 2671–6. doi:10.1073/pnas.0508955103. PMID 16478804.
- Malicet C, Dagorn JC, Neira JL, Iovanna JL (2006). "p8 and prothymosin alpha: unity is strength". Cell Cycle. 5 (8): 829–30. PMID 16628001.
- Jiang WG, Davies G, Martin TA; et al. (2007). "Com-1/p8 acts as a putative tumour suppressor in prostate cancer". Int. J. Mol. Med. 18 (5): 981–6. PMID 17016631.
- Ishida M, Miyamoto M, Naitoh S; et al. (2007). "The SYT-SSX fusion protein down-regulates the cell proliferation regulator COM1 in t(x;18) synovial sarcoma". Mol. Cell. Biol. 27 (4): 1348–55. doi:10.1128/MCB.00658-06. PMID 17101797.
- Goruppi S, Patten RD, Force T, Kyriakis JM (2007). "Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction". Mol. Cell. Biol. 27 (3): 993–1006. doi:10.1128/MCB.00996-06. PMID 17116693.
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