PCYT1A

Phosphate cytidylyltransferase 1, choline, alpha
File:PBB Protein PCYT1A image.jpg PDB rendering based on 1peh.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1peh​
Identifiers
Symbols	PCYT1A ; CT; CTPCT; PCYT1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3680
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE PCYT1A 204209 at tn.png
File:PBB GE PCYT1A 204210 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Phosphate cytidylyltransferase 1, choline, alpha, also known as PCYT1A, is a human gene.

Further reading

• Hunt AN, Normand CS, Postle AD (1990). "CTP:cholinephosphate cytidylyltransferase in human and rat lung: association in vitro with cytoskeletal actin". Biochim. Biophys. Acta. 1043 (1): 19–26. PMID 2155660.CS1 maint: Multiple names: authors list (link)
• Vance JE, Vance DE (1988). "Does rat liver Golgi have the capacity to synthesize phospholipids for lipoprotein secretion?". J. Biol. Chem. 263 (12): 5898–909. PMID 2833521.
• Weinhold PA, Feldman DA (1995). "Fatty acids promote the formation of complexes between choline-phosphate cytidylyltransferase and cytidylyltransferase binding protein". Arch. Biochem. Biophys. 318 (1): 147–56. doi:10.1006/abbi.1995.1215. PMID 7726555.
• Kalmar GB, Kay RJ, LaChance AC, Cornell RB (1994). "Primary structure and expression of a human CTP:phosphocholine cytidylyltransferase". Biochim. Biophys. Acta. 1219 (2): 328–34. PMID 7918629.CS1 maint: Multiple names: authors list (link)
• Johnson JE, Cornell RB (1994). "Membrane-binding amphipathic alpha-helical peptide derived from CTP:phosphocholine cytidylyltransferase". Biochemistry. 33 (14): 4327–35. PMID 8155650.
• Dunne SJ, Cornell RB, Johnson JE; et al. (1996). "Structure of the membrane binding domain of CTP:phosphocholine cytidylyltransferase". Biochemistry. 35 (37): 11975–84. doi:10.1021/bi960821+. PMID 8810902.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Arnold RS, DePaoli-Roach AA, Cornell RB (1997). "Binding of CTP:phosphocholine cytidylyltransferase to lipid vesicles: diacylglycerol and enzyme dephosphorylation increase the affinity for negatively charged membranes". Biochemistry. 36 (20): 6149–56. doi:10.1021/bi970023z. PMID 9166786.CS1 maint: Multiple names: authors list (link)
• Yang J, Wang J, Tseu I; et al. (1997). "Identification of an 11-residue portion of CTP-phosphocholine cytidylyltransferase that is required for enzyme-membrane interactions". Biochem. J. 325 ( Pt 1): 29–38. PMID 9224626.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lykidis A, Baburina I, Jackowski S (1999). "Distribution of CTP:phosphocholine cytidylyltransferase (CCT) isoforms. Identification of a new CCTbeta splice variant". J. Biol. Chem. 274 (38): 26992–7001. PMID 10480912.CS1 maint: Multiple names: authors list (link)
• Lagace TA, Miller JR, Ridgway ND (2002). "Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis". Mol. Cell. Biol. 22 (13): 4851–62. PMID 12052891.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Guenther MG, Yu J, Kao GD; et al. (2003). "Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex". Genes Dev. 16 (24): 3130–5. doi:10.1101/gad.1037502. PMID 12502735.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xie M, Smith JL, Ding Z; et al. (2004). "Membrane binding modulates the quaternary structure of CTP:phosphocholine cytidylyltransferase". J. Biol. Chem. 279 (27): 28817–25. doi:10.1074/jbc.M403311200. PMID 15069071.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Villén J, Gerber SA; et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Enaw JO, Zhu H, Yang W; et al. (2007). "CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population". BMC medicine. 4: 36. doi:10.1186/1741-7015-4-36. PMID 17184542.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)