PDCD10

Programmed cell death 10
Identifiers
Symbols	PDCD10 ; CCM3; MGC1212; MGC24477; TFAR15
External IDs	Template:OMIM5 Template:MGI HomoloGene: 10505
Gene ontology Biological process Template:GNF GO
RNA expression pattern
File:PBB GE PDCD10 210907 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Programmed cell death 10, also known as PDCD10, is a human gene.

This gene encodes a protein, originally identified in a premyeloid cell line, with similarity to proteins that participate in apoptosis. Three alternative transcripts encoding the same protein, differing only in their 5' UTRs, have been identified for this gene.

Further reading

• Craig HD, Günel M, Cepeda O; et al. (1998). "Multilocus linkage identifies two new loci for a mendelian form of stroke, cerebral cavernous malformation, at 7p15-13 and 3q25.2-27". Hum. Mol. Genet. 7 (12): 1851–8. PMID 9811928.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bergametti F, Denier C, Labauge P; et al. (2005). "Mutations within the programmed cell death 10 gene cause cerebral cavernous malformations". Am. J. Hum. Genet. 76 (1): 42–51. doi:10.1086/426952. PMID 15543491.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Guclu B, Ozturk AK, Pricola KL; et al. (2006). "Cerebral venous malformations have distinct genetic origin from cerebral cavernous malformations". Stroke. 36 (11): 2479–80. doi:10.1161/01.STR.0000183616.99139.d3. PMID 16239636.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Guclu B, Ozturk AK, Pricola KL; et al. (2006). "Mutations in apoptosis-related gene, PDCD10, cause cerebral cavernous malformation 3". Neurosurgery. 57 (5): 1008–13. PMID 16284570.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liquori CL, Berg MJ, Squitieri F; et al. (2006). "Low frequency of PDCD10 mutations in a panel of CCM3 probands: potential for a fourth CCM locus". Hum. Mutat. 27 (1): 118. doi:10.1002/humu.9389. PMID 16329096.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Verlaan DJ, Roussel J, Laurent SB; et al. (2006). "CCM3 mutations are uncommon in cerebral cavernous malformations". Neurology. 65 (12): 1982–3. doi:10.1212/01.wnl.0000188903.75144.49. PMID 16380626.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tsang HT, Connell JW, Brown SE; et al. (2006). "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003. PMID 16730941.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Labauge P, Krivosic V, Denier C; et al. (2006). "Frequency of retinal cavernomas in 60 patients with familial cerebral cavernomas: a clinical and genetic study". Arch. Ophthalmol. 124 (6): 885–6. doi:10.1001/archopht.124.6.885. PMID 16769843.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen PY, Chang WS, Chou RH; et al. (2007). "Two non-homologous brain diseases-related genes, SERPINI1 and PDCD10, are tightly linked by an asymmetric bidirectional promoter in an evolutionarily conserved manner". BMC Mol. Biol. 8: 2. doi:10.1186/1471-2199-8-2. PMID 17212813.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ma X, Zhao H, Shan J; et al. (2007). "PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway". Mol. Biol. Cell. 18 (6): 1965–78. doi:10.1091/mbc.E06-07-0608. PMID 17360971.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)