PDE6D

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Phosphodiesterase 6D, cGMP-specific, rod, delta
File:PBB Protein PDE6D image.jpg
PDB rendering based on 1ksg.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols PDE6D ; PDED
External IDs Template:OMIM5 Template:MGI HomoloGene1954
RNA expression pattern
File:PBB GE PDE6D 204091 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Phosphodiesterase 6D, cGMP-specific, rod, delta, also known as PDE6D, is a human gene.[1]


References

  1. "Entrez Gene: PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta".

Further reading

  • Ershova G, Derré J, Chételin S; et al. (1998). "cDNA sequence, genomic organization and mapping of PDE6D, the human gene encoding the delta subunit of the cGMP phosphodiesterase of retinal rod cells to chromosome 2q36". Cytogenet. Cell Genet. 79 (1–2): 139–41. PMID 9533031.
  • Li N, Florio SK, Pettenati MJ; et al. (1998). "Characterization of human and mouse rod cGMP phosphodiesterase delta subunit (PDE6D) and chromosomal localization of the human gene". Genomics. 49 (1): 76–82. doi:10.1006/geno.1998.5210. PMID 9570951.
  • Marzesco AM, Galli T, Louvard D, Zahraoui A (1998). "The rod cGMP phosphodiesterase delta subunit dissociates the small GTPase Rab13 from membranes". J. Biol. Chem. 273 (35): 22340–5. PMID 9712853.
  • Lorenz B, Migliaccio C, Lichtner P; et al. (1998). "Cloning and gene structure of the rod cGMP phosphodiesterase delta subunit gene (PDED) in man and mouse". Eur. J. Hum. Genet. 6 (3): 283–90. doi:10.1038/sj.ejhg.5200215. PMID 9781033.
  • Linari M, Ueffing M, Manson F; et al. (1999). "The retinitis pigmentosa GTPase regulator, RPGR, interacts with the delta subunit of rod cyclic GMP phosphodiesterase". Proc. Natl. Acad. Sci. U.S.A. 96 (4): 1315–20. PMID 9990021.
  • Mou H, Grazio HJ, Cook TA; et al. (1999). "cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its gamma and delta subunits". J. Biol. Chem. 274 (26): 18813–20. PMID 10373499.
  • Linari M, Hanzal-Bayer M, Becker J (1999). "The delta subunit of rod specific cyclic GMP phosphodiesterase, PDE delta, interacts with the Arf-like protein Arl3 in a GTP specific manner". FEBS Lett. 458 (1): 55–9. PMID 10518933.
  • Nancy V, Callebaut I, El Marjou A, de Gunzburg J (2002). "The delta subunit of retinal rod cGMP phosphodiesterase regulates the membrane association of Ras and Rap GTPases". J. Biol. Chem. 277 (17): 15076–84. doi:10.1074/jbc.M109983200. PMID 11786539.
  • Hanzal-Bayer M, Renault L, Roversi P; et al. (2002). "The complex of Arl2-GTP and PDE delta: from structure to function". EMBO J. 21 (9): 2095–106. doi:10.1093/emboj/21.9.2095. PMID 11980706.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Stelzl U, Worm U, Lalowski M; et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.
  • Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  • Wilson SJ, Smyth EM (2006). "Internalization and recycling of the human prostacyclin receptor is modulated through its isoprenylation-dependent interaction with the delta subunit of cGMP phosphodiesterase 6". J. Biol. Chem. 281 (17): 11780–6. doi:10.1074/jbc.M513110200. PMID 16527812.

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