PDE7A

Phosphodiesterase 7A
File:PBB Protein PDE7A image.jpg PDB rendering based on 1zkl.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1zkl​
Identifiers
Symbols	PDE7A ; HCP1; PDE7
External IDs	Template:OMIM5 Template:MGI HomoloGene: 1956
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE PDE7A gnf1h10851 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Phosphodiesterase 7A, also known as PDE7A, is a human gene.

Further reading

• Milatovich A, Bolger G, Michaeli T, Francke U (1994). "Chromosome localizations of genes for five cAMP-specific phosphodiesterases in man and mouse". Somat. Cell Mol. Genet. 20 (2): 75–86. PMID 8009369.CS1 maint: Multiple names: authors list (link)
• Michaeli T, Bloom TJ, Martins T; et al. (1993). "Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae". J. Biol. Chem. 268 (17): 12925–32. PMID 8389765.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Han P, Zhu X, Michaeli T (1997). "Alternative splicing of the high affinity cAMP-specific phosphodiesterase (PDE7A) mRNA in human skeletal muscle and heart". J. Biol. Chem. 272 (26): 16152–7. PMID 9195912.CS1 maint: Multiple names: authors list (link)
• Han P, Fletcher CF, Copeland NG; et al. (1998). "Assignment of the mouse Pde7A gene to the proximal region of chromosome 3 and of the human PDE7A gene to chromosome 8q13". Genomics. 48 (2): 275–6. doi:10.1006/geno.1997.5168. PMID 9521885.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhou L, Thompson WJ, Potter DE (1999). "Multiple cyclic nucleotide phosphodiesterases in human trabecular meshwork cells". Invest. Ophthalmol. Vis. Sci. 40 (8): 1745–52. PMID 10393044.CS1 maint: Multiple names: authors list (link)
• Miró X, Casacuberta JM, Gutiérrez-López MD; et al. (2000). "Phosphodiesterases 4D and 7A splice variants in the response of HUVEC cells to TNF-alpha(1)". Biochem. Biophys. Res. Commun. 274 (2): 415–21. doi:10.1006/bbrc.2000.3146. PMID 10913353.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zauli G, Milani D, Mirandola P; et al. (2001). "HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway". FASEB J. 15 (2): 483–91. doi:10.1096/fj.00-0354com. PMID 11156964.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Glavas NA, Ostenson C, Schaefer JB; et al. (2001). "T cell activation up-regulates cyclic nucleotide phosphodiesterases 8A1 and 7A3". Proc. Natl. Acad. Sci. U.S.A. 98 (11): 6319–24. doi:10.1073/pnas.101131098. PMID 11371644.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lee R, Wolda S, Moon E; et al. (2002). "PDE7A is expressed in human B-lymphocytes and is up-regulated by elevation of intracellular cAMP". Cell. Signal. 14 (3): 277–84. PMID 11812656.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nakata A, Ogawa K, Sasaki T; et al. (2002). "Potential role of phosphodiesterase 7 in human T cell function: comparative effects of two phosphodiesterase inhibitors". Clin. Exp. Immunol. 128 (3): 460–6. PMID 12067300.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Smith SJ, Brookes-Fazakerley S, Donnelly LE; et al. (2003). "Ubiquitous expression of phosphodiesterase 7A in human proinflammatory and immune cells". Am. J. Physiol. Lung Cell Mol. Physiol. 284 (2): L279–89. doi:10.1152/ajplung.00170.2002. PMID 12388353.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Torras-Llort M, Azorín F (2003). "Functional characterization of the human phosphodiesterase 7A1 promoter". Biochem. J. 373 (Pt 3): 835–43. doi:10.1042/BJ20021829. PMID 12737631.
• Wang H, Liu Y, Chen Y; et al. (2005). "Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7". J. Biol. Chem. 280 (35): 30949–55. doi:10.1074/jbc.M504398200. PMID 15994308.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)