PEX13
Peroxisome biogenesis factor 13 | |||||||||||||
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File:PBB Protein PEX13 image.jpg PDB rendering based on 1wxu. | |||||||||||||
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Identifiers | |||||||||||||
Symbols | PEX13 ; NALD; ZWS | ||||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 1967 | ||||||||||||
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RNA expression pattern | |||||||||||||
File:PBB GE PEX13 205246 at tn.png | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Template:GNF Ortholog box | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | n/a | n/a | |||||||||||
Ensembl | n/a | n/a | |||||||||||
UniProt | n/a | n/a | |||||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||||
RefSeq (protein) | n/a | n/a | |||||||||||
Location (UCSC) | n/a | n/a | |||||||||||
PubMed search | n/a | n/a |
Peroxisome biogenesis factor 13, also known as PEX13, is a human gene.[1]
References
Further reading
- Gould SJ, Kalish JE, Morrell JC; et al. (1996). "Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor". J. Cell Biol. 135 (1): 85–95. PMID 8858165.
- Albertini M, Rehling P, Erdmann R; et al. (1997). "Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways". Cell. 89 (1): 83–92. PMID 9094717.
- Fransen M, Terlecky SR, Subramani S (1998). "Identification of a human PTS1 receptor docking protein directly required for peroxisomal protein import". Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8087–92. PMID 9653144.
- Björkman J, Stetten G, Moore CS; et al. (1999). "Genomic structure of PEX13, a candidate peroxisome biogenesis disorder gene". Genomics. 54 (3): 521–8. doi:10.1006/geno.1998.5520. PMID 9878256.
- Girzalsky W, Rehling P, Stein K; et al. (1999). "Involvement of Pex13p in Pex14p localization and peroxisomal targeting signal 2-dependent protein import into peroxisomes". J. Cell Biol. 144 (6): 1151–62. PMID 10087260.
- Shimozawa N, Suzuki Y, Zhang Z; et al. (1999). "Nonsense and temperature-sensitive mutations in PEX13 are the cause of complementation group H of peroxisome biogenesis disorders". Hum. Mol. Genet. 8 (6): 1077–83. PMID 10332040.
- Toyama R, Mukai S, Itagaki A; et al. (2000). "Isolation, characterization and mutation analysis of PEX13-defective Chinese hamster ovary cell mutants". Hum. Mol. Genet. 8 (9): 1673–81. PMID 10441330.
- Liu Y, Björkman J, Urquhart A; et al. (1999). "PEX13 is mutated in complementation group 13 of the peroxisome-biogenesis disorders". Am. J. Hum. Genet. 65 (3): 621–34. PMID 10441568.
- Sacksteder KA, Jones JM, South ST; et al. (2000). "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis". J. Cell Biol. 148 (5): 931–44. PMID 10704444.
- Fransen M, Wylin T, Brees C; et al. (2001). "Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences". Mol. Cell. Biol. 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. PMID 11390669.
- Jones JM, Morrell JC, Gould SJ (2001). "Multiple distinct targeting signals in integral peroxisomal membrane proteins". J. Cell Biol. 153 (6): 1141–50. PMID 11402059.
- Otera H, Setoguchi K, Hamasaki M; et al. (2002). "Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import". Mol. Cell. Biol. 22 (6): 1639–55. PMID 11865044.
- Fransen M, Brees C, Ghys K; et al. (2002). "Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay". Mol. Cell Proteomics. 1 (3): 243–52. PMID 12096124.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Fransen M, Vastiau I, Brees C; et al. (2004). "Potential role for Pex19p in assembly of PTS-receptor docking complexes". J. Biol. Chem. 279 (13): 12615–24. doi:10.1074/jbc.M304941200. PMID 14715663.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Hashimoto K, Kato Z, Nagase T; et al. (2005). "Molecular mechanism of a temperature-sensitive phenotype in peroxisomal biogenesis disorder". Pediatr. Res. 58 (2): 263–9. doi:10.1203/01.PDR.0000169984.89199.69. PMID 16006427.
- Nguyen T, Bjorkman J, Paton BC, Crane DI (2006). "Failure of microtubule-mediated peroxisome division and trafficking in disorders with reduced peroxisome abundance". J. Cell. Sci. 119 (Pt 4): 636–45. doi:10.1242/jcs.02776. PMID 16449325.
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