PGA5

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Pepsinogen 5, group I (pepsinogen A)
File:PBB Protein PGA5 image.jpg
PDB rendering based on 1flh.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols PGA5 ;
External IDs Template:OMIM5 HomoloGene68135
RNA expression pattern
File:PBB GE PGA5 213265 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Pepsinogen 5, group I (pepsinogen A), also known as PGA5, is a human gene.[1]


References

  1. "Entrez Gene: PGA5 pepsinogen 5, group I (pepsinogen A)".

Further reading

  • Ichinose M, Miki K, Wong RN; et al. (1991). "Methylation and expression of human pepsinogen genes in normal tissues and their alteration in stomach cancer". Jpn. J. Cancer Res. 82 (6): 686–92. PMID 1906854.
  • Ichihara Y, Sogawa K, Takahashi K (1986). "Isolation of human, swine, and rat prepepsinogens and calf preprochymosin, and determination of the primary structures of their NH2-terminal signal sequences". J. Biochem. 98 (2): 483–92. PMID 2415509.
  • Athauda SB, Tanji M, Kageyama T, Takahashi K (1990). "A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins". J. Biochem. 106 (5): 920–7. PMID 2515193.
  • Hengels KJ, Strohmeyer G (1990). "Pepsinogens A and C: purification from human gastric mucosa and determination in serum by optimized radioimmunoassays". Zeitschrift für Gastroenterologie. 27 (8): 406–11. PMID 2609705.
  • Evers MP, Zelle B, Bebelman JP; et al. (1989). "Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family". Genomics. 4 (3): 232–9. PMID 2714789.
  • ten Kate RW, Pals G, Donker AJ; et al. (1989). "Tubular handling of pepsinogen A and C in man: evidence for two distinct tubular reabsorption mechanisms for low molecular weight proteins in man". Nephron. 53 (3): 223–8. PMID 2797342.
  • ten Kate RW, Pals G, Eriksson AW; et al. (1989). "The renal metabolism of pepsinogen A and C in man". Clin. Nephrol. 31 (2): 103–6. PMID 2920466.
  • Evers MP, Zelle B, Peeper DS; et al. (1987). "Molecular cloning of a pair of human pepsinogen A genes which differ by a Glu----Lys mutation in the activation peptide". Hum. Genet. 77 (2): 182–7. PMID 3115885.
  • Pals G, Eriksson AW, Pronk JC; et al. (1989). "Differential expression of pepsinogen isozymogens in a patient with Barrett esophagus". Clin. Genet. 34 (2): 90–7. PMID 3191614.
  • Foltmann B (1989). "Activation of human pepsinogens". FEBS Lett. 241 (1–2): 69–72. PMID 3197840.
  • Westerveld BD, Pals G, Bosma A; et al. (1987). "Gastric proteases in Barrett's esophagus". Gastroenterology. 93 (4): 774–8. PMID 3305135.
  • Nakai H, Byers MG, Shows TB, Taggart RT (1987). "Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization". Cytogenet. Cell Genet. 43 (3–4): 215–7. PMID 3467902.
  • Sogawa K, Fujii-Kuriyama Y, Mizukami Y; et al. (1983). "Primary structure of human pepsinogen gene". J. Biol. Chem. 258 (8): 5306–11. PMID 6300126.
  • Fujinaga M, Chernaia MM, Tarasova NI; et al. (1995). "Crystal structure of human pepsin and its complex with pepstatin". Protein Sci. 4 (5): 960–72. PMID 7663352.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
  • Zwiers A, ten Dam MA, Crusius JB; et al. (1994). "The renal handling of pepsinogen A isozymogens in man". Clin. Nephrol. 41 (3): 153–8. PMID 8187358.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
  • Plebani M, Basso D, Navaglia F, DiMario F (1998). "Helicobacter pylori genotypes influence serum pepsinogen C levels". Helicobacter. 2 (4): 172–5. PMID 9421118.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.

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