PGLYRP2

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Peptidoglycan recognition protein 2
Identifiers
Symbols PGLYRP2 ; HMFT0141; PGLYRPL; PGRP-L; PGRPL; TAGL-like; tagL; tagL-alpha; tagl-beta
External IDs Template:OMIM5 HomoloGene49671
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Peptidoglycan recognition protein 2, also known as PGLYRP2, is a human gene.[1]

Peptidoglycan recognition proteins, such as PGRPL, are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls.[supplied by OMIM][1]

References

  1. 1.0 1.1 "Entrez Gene: PGLYRP2 peptidoglycan recognition protein 2".

Further reading

  • De Pauw P, Neyt C, Vanderwinkel E; et al. (1995). "Characterization of human serum N-acetylmuramyl-L-alanine amidase purified by affinity chromatography". Protein Expr. Purif. 6 (3): 371–8. PMID 7663175.
  • Dehal P, Predki P, Olsen AS; et al. (2001). "Human chromosome 19 and related regions in mouse: conservative and lineage-specific evolution". Science. 293 (5527): 104–11. doi:10.1126/science.1060310. PMID 11441184.
  • Liu C, Xu Z, Gupta D, Dziarski R (2001). "Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules". J. Biol. Chem. 276 (37): 34686–94. doi:10.1074/jbc.M105566200. PMID 11461926.
  • Xu XR, Huang J, Xu ZG; et al. (2002). "Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver". Proc. Natl. Acad. Sci. U.S.A. 98 (26): 15089–94. doi:10.1073/pnas.241522398. PMID 11752456.
  • Kibardin AV, Mirkina II, Zakeeva IR; et al. (2003). "[Expression analysis of proteins encoded by genes of the tag7/tagL (PGRP-S,L) family in human peripheral blood cells]". Genetika. 39 (2): 244–9. PMID 12669421.
  • Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID 12754519.
  • Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
  • Wang ZM, Li X, Cocklin RR; et al. (2004). "Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase". J. Biol. Chem. 278 (49): 49044–52. doi:10.1074/jbc.M307758200. PMID 14506276.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Yamada S, Ohira M, Horie H; et al. (2004). "Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas". Oncogene. 23 (35): 5901–11. doi:10.1038/sj.onc.1207782. PMID 15221005.
  • Xu M, Wang Z, Locksley RM (2004). "Innate immune responses in peptidoglycan recognition protein L-deficient mice". Mol. Cell. Biol. 24 (18): 7949–57. doi:10.1128/MCB.24.18.7949-7957.2004. PMID 15340057.
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMID 15340161.
  • Zhang Y, van der Fits L, Voerman JS; et al. (2005). "Identification of serum N-acetylmuramoyl-l-alanine amidase as liver peptidoglycan recognition protein 2". Biochim. Biophys. Acta. 1752 (1): 34–46. doi:10.1016/j.bbapap.2005.07.001. PMID 16054449.
  • Wang H, Gupta D, Li X, Dziarski R (2005). "Peptidoglycan recognition protein 2 (N-acetylmuramoyl-L-Ala amidase) is induced in keratinocytes by bacteria through the p38 kinase pathway". Infect. Immun. 73 (11): 7216–25. doi:10.1128/IAI.73.11.7216-7225.2005. PMID 16239516.
  • Liu T, Qian WJ, Gritsenko MA; et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.
  • Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
  • Li X, Wang S, Wang H, Gupta D (2006). "Differential expression of peptidoglycan recognition protein 2 in the skin and liver requires different transcription factors". J. Biol. Chem. 281 (30): 20738–48. doi:10.1074/jbc.M601017200. PMID 16714290.

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