PLSCR1
| Phospholipid scramblase 1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | PLSCR1 ; MMTRA1B | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 41418 | ||||||||||
| |||||||||||
| RNA expression pattern | |||||||||||
| File:PBB GE PLSCR1 202446 s at tn.png | |||||||||||
| File:PBB GE PLSCR1 202430 s at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Phospholipid scramblase 1, also known as PLSCR1, is a human gene.[1]
See also
References
Further reading
- Bassé F, Stout JG, Sims PJ, Wiedmer T (1996). "Isolation of an erythrocyte membrane protein that mediates Ca2+-dependent transbilayer movement of phospholipid". J. Biol. Chem. 271 (29): 17205–10. PMID 8663431.
- Zhou Q, Zhao J, Stout JG; et al. (1997). "Molecular cloning of human plasma membrane phospholipid scramblase. A protein mediating transbilayer movement of plasma membrane phospholipids". J. Biol. Chem. 272 (29): 18240–4. PMID 9218461.
- Zhou Q, Sims PJ, Wiedmer T (1998). "Identity of a conserved motif in phospholipid scramblase that is required for Ca2+-accelerated transbilayer movement of membrane phospholipids". Biochemistry. 37 (8): 2356–60. doi:10.1021/bi972625o. PMID 9485382.
- Zhao J, Zhou Q, Wiedmer T, Sims PJ (1998). "Palmitoylation of phospholipid scramblase is required for normal function in promoting Ca2+-activated transbilayer movement of membrane phospholipids". Biochemistry. 37 (18): 6361–6. doi:10.1021/bi980218m. PMID 9572851.
- Kasukabe T, Kobayashi H, Kaneko Y; et al. (1998). "Identity of human normal counterpart (MmTRA1b) of mouse leukemogenesis-associated gene (MmTRA1a) product as plasma membrane phospholipid scramblase and chromosome mapping of the human MmTRA1b/phospholipid scramblase gene". Biochem. Biophys. Res. Commun. 249 (2): 449–55. doi:10.1006/bbrc.1998.9190. PMID 9712717.
- Zhou Q, Zhao J, Al-Zoghaibi F; et al. (2000). "Transcriptional control of the human plasma membrane phospholipid scramblase 1 gene is mediated by interferon-alpha". Blood. 95 (8): 2593–9. PMID 10753839.
- Frasch SC, Henson PM, Kailey JM; et al. (2000). "Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta". J. Biol. Chem. 275 (30): 23065–73. doi:10.1074/jbc.M003116200. PMID 10770950.
- Tseng CC, Tseng CP (2000). "Identification of a novel secretory leukocyte protease inhibitor-binding protein involved in membrane phospholipid movement". FEBS Lett. 475 (3): 232–6. PMID 10869562.
- Wiedmer T, Zhou Q, Kwoh DY, Sims PJ (2000). "Identification of three new members of the phospholipid scramblase gene family". Biochim. Biophys. Acta. 1467 (1): 244–53. PMID 10930526.
- Sun J, Zhao J, Schwartz MA; et al. (2001). "c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1". J. Biol. Chem. 276 (31): 28984–90. doi:10.1074/jbc.M102505200. PMID 11390389.
- Silverman RH, Halloum A, Zhou A; et al. (2002). "Suppression of ovarian carcinoma cell growth in vivo by the interferon-inducible plasma membrane protein, phospholipid scramblase 1". Cancer Res. 62 (2): 397–402. PMID 11809687.
- Sun J, Nanjundan M, Pike LJ; et al. (2002). "Plasma membrane phospholipid scramblase 1 is enriched in lipid rafts and interacts with the epidermal growth factor receptor". Biochemistry. 41 (20): 6338–45. PMID 12009895.
- Zhou Q, Zhao J, Wiedmer T, Sims PJ (2002). "Normal hemostasis but defective hematopoietic response to growth factors in mice deficient in phospholipid scramblase 1". Blood. 99 (11): 4030–8. doi:10.1182/blood-2001-12-0271. PMID 12010804.
- Xu YC, Wu RF, Gu Y; et al. (2002). "Involvement of TRAF4 in oxidative activation of c-Jun N-terminal kinase". J. Biol. Chem. 277 (31): 28051–7. doi:10.1074/jbc.M202665200. PMID 12023963.
- Nakamaki T, Okabe-Kado J, Yamamoto-Yamaguchi Y; et al. (2002). "Role of MmTRA1b/phospholipid scramblase1 gene expression in the induction of differentiation of human myeloid leukemia cells into granulocytes". Exp. Hematol. 30 (5): 421–9. PMID 12031648.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Wiedmer T, Zhao J, Nanjundan M, Sims PJ (2003). "Palmitoylation of phospholipid scramblase 1 controls its distribution between nucleus and plasma membrane". Biochemistry. 42 (5): 1227–33. doi:10.1021/bi026679w. PMID 12564925.
- Kametaka S, Shibata M, Moroe K; et al. (2003). "Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE))". J. Biol. Chem. 278 (17): 15239–45. doi:10.1074/jbc.M208611200. PMID 12586838.
- Rami A, Sims J, Botez G, Winckler J (2003). "Spatial resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia". Neurochem. Int. 43 (1): 79–87. PMID 12605885.
- Nanjundan M, Sun J, Zhao J; et al. (2003). "Plasma membrane phospholipid scramblase 1 promotes EGF-dependent activation of c-Src through the epidermal growth factor receptor". J. Biol. Chem. 278 (39): 37413–8. doi:10.1074/jbc.M306182200. PMID 12871937.
 | This protein-related article is a stub. You can help Wikipedia by expanding it. |