POLD1
Polymerase (DNA directed), delta 1, catalytic subunit 125kDa | |||||||||||
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Identifiers | |||||||||||
Symbols | POLD1 ; CDC2; POLD | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 2014 | ||||||||||
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RNA expression pattern | |||||||||||
File:PBB GE POLD1 203422 at tn.png | |||||||||||
More reference expression data | |||||||||||
Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
Polymerase (DNA directed), delta 1, catalytic subunit 125kDa, also known as POLD1, is a human gene.[1]
References
Further reading
- Kemper RR, Ahn ER, Zhang P; et al. (1992). "Human DNA polymerase delta gene maps to region 19q13.3-q13.4 by in situ hybridization". Genomics. 14 (1): 205–6. PMID 1427831.
- Yang CL, Chang LS, Zhang P; et al. (1992). "Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase delta". Nucleic Acids Res. 20 (4): 735–45. PMID 1542570.
- Chung DW, Zhang JA, Tan CK; et al. (1992). "Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene". Proc. Natl. Acad. Sci. U.S.A. 88 (24): 11197–201. PMID 1722322.
- Popanda O, Thielmann HW (1992). "The function of DNA polymerases in DNA repair synthesis of ultraviolet-irradiated human fibroblasts". Biochim. Biophys. Acta. 1129 (2): 155–60. PMID 1730053.
- Lee MY, Toomey NL (1987). "Human placental DNA polymerase delta: identification of a 170-kilodalton polypeptide by activity staining and immunoblotting". Biochemistry. 26 (4): 1076–85. PMID 2436659.
- Dresler SL, Gowans BJ, Robinson-Hill RM, Hunting DJ (1989). "Involvement of DNA polymerase delta in DNA repair synthesis in human fibroblasts at late times after ultraviolet irradiation". Biochemistry. 27 (17): 6379–83. PMID 3146346.
- Nishida C, Reinhard P, Linn S (1988). "DNA repair synthesis in human fibroblasts requires DNA polymerase delta". J. Biol. Chem. 263 (1): 501–10. PMID 3335506.
- Hindges R, Hübscher U (1997). "Cloning, chromosomal localization, and interspecies interaction of mouse DNA polymerase delta small subunit (PolD2)". Genomics. 44 (1): 45–51. doi:10.1006/geno.1997.4838. PMID 9286699.
- Wu SM, Zhang P, Zeng XR; et al. (1998). "Characterization of the p125 subunit of human DNA polymerase delta and its deletion mutants. Interaction with cyclin-dependent kinase-cyclins". J. Biol. Chem. 273 (16): 9561–9. PMID 9545286.
- Coll JM, Hickey RJ, Cronkey EA; et al. (1998). "Mapping specific protein-protein interactions within the core component of the breast cell DNA synthesome". Oncol. Res. 9 (11–12): 629–39. PMID 9563011.
- Fox G, Popanda O, Thielmann HW (1998). "Evidence for reduced copying fidelity of DNA polymerases alpha, delta, and epsilon from Novikoff hepatoma cells". J. Cancer Res. Clin. Oncol. 123 (11–12): 659–68. PMID 9620226.
- Kim ST, Lim DS, Canman CE, Kastan MB (2000). "Substrate specificities and identification of putative substrates of ATM kinase family members". J. Biol. Chem. 274 (53): 37538–43. PMID 10608806.
- Mo J, Liu L, Leon A; et al. (2000). "Evidence that DNA polymerase delta isolated by immunoaffinity chromatography exhibits high-molecular weight characteristics and is associated with the KIAA0039 protein and RPA". Biochemistry. 39 (24): 7245–54. PMID 10852724.
- Budworth H, Dianova II, Podust VN, Dianov GL (2002). "Repair of clustered DNA lesions. Sequence-specific inhibition of long-patch base excision repair be 8-oxoguanine". J. Biol. Chem. 277 (24): 21300–5. doi:10.1074/jbc.M201918200. PMID 11923315.
- Ohta S, Shiomi Y, Sugimoto K; et al. (2002). "A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein". J. Biol. Chem. 277 (43): 40362–7. doi:10.1074/jbc.M206194200. PMID 12171929.
- Smith RW, Nasheuer HP (2002). "Control of complex formation of DNA polymerase alpha-primase and cell-free DNA replication by the C-terminal amino acids of the largest subunit p180". FEBS Lett. 527 (1–3): 143–6. PMID 12220650.
- Matheos D, Ruiz MT, Price GB, Zannis-Hadjopoulos M (2002). "Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication". Biochim. Biophys. Acta. 1578 (1–3): 59–72. PMID 12393188.
- Xie B, Mazloum N, Liu L; et al. (2002). "Reconstitution and characterization of the human DNA polymerase delta four-subunit holoenzyme". Biochemistry. 41 (44): 13133–42. PMID 12403614.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Shevelev IV, Ramadan K, Hübscher U (2004). "The TREX2 3'-->5' exonuclease physically interacts with DNA polymerase delta and increases its accuracy". ScientificWorldJournal. 2: 275–81. doi:10.1100/tsw.2002.99. PMID 12806015.
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