PPP3CB

Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform
Identifiers
Symbols	PPP3CB ; CALNA2; CALNB
External IDs	Template:OMIM5 Template:MGI HomoloGene: 56429
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE PPP3CB 209817 at tn.png
File:PBB GE PPP3CB 202432 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform, also known as PPP3CB, is a human gene.

Further reading

• Chen MX, Chen YH, Cohen PT (1992). "Polymerase chain reactions using Saccharomyces, Drosophila and human DNA predict a large family of protein serine/threonine phosphatases". FEBS Lett. 306 (1): 54–8. PMID 1321058.CS1 maint: Multiple names: authors list (link)
• Giri PR, Higuchi S, Kincaid RL (1992). "Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit". Biochem. Biophys. Res. Commun. 181 (1): 252–8. PMID 1659808.CS1 maint: Multiple names: authors list (link)
• McPartlin AE, Barker HM, Cohen PT (1991). "Identification of a third alternatively spliced cDNA encoding the catalytic subunit of protein phosphatase 2B beta". Biochim. Biophys. Acta. 1088 (2): 308–10. PMID 1848109.CS1 maint: Multiple names: authors list (link)
• Guerini D, Klee CB (1990). "Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain". Proc. Natl. Acad. Sci. U.S.A. 86 (23): 9183–7. PMID 2556704.
• Guerini D, Krinks MH, Sikela JM; et al. (1990). "Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase". DNA. 8 (9): 675–82. PMID 2558868.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shibasaki F, McKeon F (1995). "Calcineurin functions in Ca(2+)-activated cell death in mammalian cells". J. Cell Biol. 131 (3): 735–43. PMID 7593193.
• Muramatsu T, Kincaid RL (1993). "Molecular cloning of a full-length cDNA encoding the catalytic subunit of human calmodulin-dependent protein phosphatase (calcineurin A alpha)". Biochim. Biophys. Acta. 1178 (1): 117–20. PMID 8392375.
• Kissinger CR, Parge HE, Knighton DR; et al. (1996). "Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex". Nature. 378 (6557): 641–4. doi:10.1038/378641a0. PMID 8524402.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang MG, Yi H, Guerini D; et al. (1997). "Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21-->q22 and 2p16-->p15 respectively". Cytogenet. Cell Genet. 72 (2–3): 236–41. PMID 8978785.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sun L, Youn HD, Loh C; et al. (1998). "Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes". Immunity. 8 (6): 703–11. PMID 9655484.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Aramburu J, Garcia-Cózar F, Raghavan A; et al. (1998). "Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT". Mol. Cell. 1 (5): 627–37. PMID 9660947.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Okamura H, Aramburu J, García-Rodríguez C; et al. (2000). "Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity". Mol. Cell. 6 (3): 539–50. PMID 11030334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Frey N, Richardson JA, Olson EN (2001). "Calsarcins, a novel family of sarcomeric calcineurin-binding proteins". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14632–7. doi:10.1073/pnas.260501097. PMID 11114196.CS1 maint: Multiple names: authors list (link)
• Esau C, Boes M, Youn HD; et al. (2001). "Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells". J. Exp. Med. 194 (10): 1449–59. PMID 11714752.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Frey N, Olson EN (2002). "Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins". J. Biol. Chem. 277 (16): 13998–4004. doi:10.1074/jbc.M200712200. PMID 11842093.
• Banerjee A, Banks AS, Nawijn MC; et al. (2002). "Cutting edge: Suppressor of cytokine signaling 3 inhibits activation of NFATp". J. Immunol. 168 (9): 4277–81. PMID 11970967.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bennasser Y, Badou A, Tkaczuk J, Bahraoui E (2003). "Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha". Virology. 303 (1): 174–80. PMID 12482669.CS1 maint: Multiple names: authors list (link)
• Genescà L, Aubareda A, Fuentes JJ; et al. (2003). "Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life". Biochem. J. 374 (Pt 2): 567–75. doi:10.1042/BJ20030267. PMID 12809556.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bell O, Gaberman E, Kilav R; et al. (2005). "The protein phosphatase calcineurin determines basal parathyroid hormone gene expression". Mol. Endocrinol. 19 (2): 516–26. doi:10.1210/me.2004-0108. PMID 15514034.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)