RAB22A
RAB22A, member RAS oncogene family | |||||||||||||
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File:PBB Protein RAB22A image.jpg PDB rendering based on 1yvd. | |||||||||||||
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Identifiers | |||||||||||||
Symbols | RAB22A ; MGC16770 | ||||||||||||
External IDs | Template:MGI HomoloGene: 10782 | ||||||||||||
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RNA expression pattern | |||||||||||||
File:PBB GE RAB22A 218360 at tn.png | |||||||||||||
File:PBB GE RAB22A 213405 at tn.png | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Template:GNF Ortholog box | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | n/a | n/a | |||||||||||
Ensembl | n/a | n/a | |||||||||||
UniProt | n/a | n/a | |||||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||||
RefSeq (protein) | n/a | n/a | |||||||||||
Location (UCSC) | n/a | n/a | |||||||||||
PubMed search | n/a | n/a |
RAB22A, member RAS oncogene family, also known as RAB22A, is a human gene.[1]
The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments.[1]
References
Further reading
- Bao S, Zhu J, Garvey WT (1999). "Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects". Horm. Metab. Res. 30 (11): 656–62. PMID 9918381.
- Bucci C, Chiariello M, Lattero D; et al. (1999). "Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1)". Biochem. Biophys. Res. Commun. 258 (3): 657–62. doi:10.1006/bbrc.1999.0651. PMID 10329441.
- Opdam FJ, Kamps G, Croes H; et al. (2000). "Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells". Eur. J. Cell Biol. 79 (5): 308–16. PMID 10887961.
- Deloukas P, Matthews LH, Ashurst J; et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
- Kauppi M, Simonsen A, Bremnes B; et al. (2002). "The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking". J. Cell. Sci. 115 (Pt 5): 899–911. PMID 11870209.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Seet LF, Liu N, Hanson BJ, Hong W (2004). "Endofin recruits TOM1 to endosomes". J. Biol. Chem. 279 (6): 4670–9. doi:10.1074/jbc.M311228200. PMID 14613930.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Weigert R, Yeung AC, Li J, Donaldson JG (2005). "Rab22a regulates the recycling of membrane proteins internalized independently of clathrin". Mol. Biol. Cell. 15 (8): 3758–70. doi:10.1091/mbc.E04-04-0342. PMID 15181155.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Mesa R, Magadán J, Barbieri A; et al. (2005). "Overexpression of Rab22a hampers the transport between endosomes and the Golgi apparatus". Exp. Cell Res. 304 (2): 339–53. doi:10.1016/j.yexcr.2004.11.017. PMID 15748882.
- Barrios-Rodiles M, Brown KR, Ozdamar B; et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
- Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Magadán JG, Barbieri MA, Mesa R; et al. (2006). "Rab22a regulates the sorting of transferrin to recycling endosomes". Mol. Cell. Biol. 26 (7): 2595–614. doi:10.1128/MCB.26.7.2595-2614.2006. PMID 16537905.
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