RAB5B
RAB5B, member RAS oncogene family | |||||||||||||
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File:PBB Protein RAB5B image.jpg PDB rendering based on 1huq. | |||||||||||||
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Identifiers | |||||||||||||
Symbols | RAB5B ; | ||||||||||||
External IDs | Template:OMIM5 HomoloGene: 88670 | ||||||||||||
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RNA expression pattern | |||||||||||||
File:PBB GE RAB5B 201276 at tn.png | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Template:GNF Ortholog box | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | n/a | n/a | |||||||||||
Ensembl | n/a | n/a | |||||||||||
UniProt | n/a | n/a | |||||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||||
RefSeq (protein) | n/a | n/a | |||||||||||
Location (UCSC) | n/a | n/a | |||||||||||
PubMed search | n/a | n/a |
RAB5B, member RAS oncogene family, also known as RAB5B, is a human gene.[1]
References
Further reading
- Wilson DB, Wilson MP (1992). "Identification and subcellular localization of human rab5b, a new member of the ras-related superfamily of GTPases". J. Clin. Invest. 89 (3): 996–1005. PMID 1541686.
- Bucci C, Lütcke A, Steele-Mortimer O; et al. (1995). "Co-operative regulation of endocytosis by three Rab5 isoforms". FEBS Lett. 366 (1): 65–71. PMID 7789520.
- Korenberg JR, Chen XN, Adams MD, Venter JC (1996). "Toward a cDNA map of the human genome". Genomics. 29 (2): 364–70. PMID 8666383.
- Bao S, Zhu J, Garvey WT (1999). "Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects". Horm. Metab. Res. 30 (11): 656–62. PMID 9918381.
- Chiariello M, Bruni CB, Bucci C (1999). "The small GTPases Rab5a, Rab5b and Rab5c are differentially phosphorylated in vitro". FEBS Lett. 453 (1–2): 20–4. PMID 10403367.
- Callaghan J, Nixon S, Bucci C; et al. (1999). "Direct interaction of EEA1 with Rab5b". Eur. J. Biochem. 265 (1): 361–6. PMID 10491193.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R; et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
- Simpson JC, Wellenreuther R, Poustka A; et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
- Tall GG, Barbieri MA, Stahl PD, Horazdovsky BF (2001). "Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1". Dev. Cell. 1 (1): 73–82. PMID 11703925.
- Saito K, Murai J, Kajiho H; et al. (2002). "A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5". J. Biol. Chem. 277 (5): 3412–8. doi:10.1074/jbc.M106276200. PMID 11733506.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Merithew E, Stone C, Eathiraj S, Lambright DG (2003). "Determinants of Rab5 interaction with the N terminus of early endosome antigen 1". J. Biol. Chem. 278 (10): 8494–500. doi:10.1074/jbc.M211514200. PMID 12493736.
- Kajiho H, Saito K, Tsujita K; et al. (2004). "RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway". J. Cell. Sci. 116 (Pt 20): 4159–68. doi:10.1242/jcs.00718. PMID 12972505.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Wiemann S, Arlt D, Huber W; et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.
- Mehrle A, Rosenfelder H, Schupp I; et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.
- Chi A, Valencia JC, Hu ZZ; et al. (2007). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes". J. Proteome Res. 5 (11): 3135–44. doi:10.1021/pr060363j. PMID 17081065.
- Hirota Y, Kuronita T, Fujita H, Tanaka Y (2007). "A role for Rab5 activity in the biogenesis of endosomal and lysosomal compartments". Biochem. Biophys. Res. Commun. 364 (1): 40–7. doi:10.1016/j.bbrc.2007.09.089. PMID 17927960.
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