RAGE (gene)
| Renal tumor antigen | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | RAGE ; MOK; RAGE1 | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 8062 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE RAGE 205130 at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Renal tumor antigen, also known as RAGE, is a human gene.[1]
References
Further reading
- Gaugler B, Brouwenstijn N, Vantomme V; et al. (1996). "A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma". Immunogenetics. 44 (5): 323–30. PMID 8781117.
- Miyata Y, Akashi M, Nishida E (1999). "Molecular cloning and characterization of a novel member of the MAP kinase superfamily". Genes Cells. 4 (5): 299–309. PMID 10421840.
- Eichmüller S, Usener D, Jochim A, Schadendorf D (2003). "mRNA expression of tumor-associated antigens in melanoma tissues and cell lines". Exp. Dermatol. 11 (4): 292–301. PMID 12190937.
- Götte K, Usener D, Riedel F; et al. (2003). "Tumor-associated antigens as possible targets for immune therapy in head and neck cancer: comparative mRNA expression analysis of RAGE and GAGE genes". Acta Otolaryngol. 122 (5): 546–52. PMID 12206267.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Yan M, Ghorab Z, Nadji M (2004). "Renal cell carcinoma antigen is expressed by yolk sac tumors and yolk sac elements of embryonal carcinomas". Appl. Immunohistochem. Mol. Morphol. 11 (2): 113–5. PMID 12777992.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Miura J, Uchigata Y, Yamamoto Y; et al. (2004). "AGE down-regulation of monocyte RAGE expression and its association with diabetic complications in type 1 diabetes". J. Diabetes Complicat. 18 (1): 53–9. doi:10.1016/S1056-8727(02)00281-7. PMID 15019601.
- Rudofsky G, Isermann B, Schilling T; et al. (2004). "A 63bp deletion in the promoter of rage correlates with a decreased risk for nephropathy in patients with type 2 diabetes". Exp. Clin. Endocrinol. Diabetes. 112 (3): 135–41. doi:10.1055/s-2004-817822. PMID 15052533.
- Uesaka T, Kageyama N (2004). "Cdx2 homeodomain protein regulates the expression of MOK, a member of the mitogen-activated protein kinase superfamily, in the intestinal epithelial cells". FEBS Lett. 573 (1–3): 147–54. doi:10.1016/j.febslet.2004.07.070. PMID 15327990.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Bierhaus A, Haslbeck KM, Humpert PM; et al. (2005). "Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily". J. Clin. Invest. 114 (12): 1741–51. doi:10.1172/JCI200418058. PMID 15599399.
- Grunau C, Sanchez C, Ehrlich M; et al. (2005). "Frequent DNA hypomethylation of human juxtacentromeric BAGE loci in cancer". Genes Chromosomes Cancer. 43 (1): 11–24. doi:10.1002/gcc.20155. PMID 15704127.
- dos Santos KG, Canani LH, Gross JL; et al. (2005). "The -374A allele of the receptor for advanced glycation end products gene is associated with a decreased risk of ischemic heart disease in African-Brazilians with type 2 diabetes". Mol. Genet. Metab. 85 (2): 149–56. doi:10.1016/j.ymgme.2005.02.010. PMID 15896660.
- Oehlrich N, Devitt G, Linnebacher M; et al. (2005). "Generation of RAGE-1 and MAGE-9 peptide-specific cytotoxic T-lymphocyte lines for transfer in patients with renal cell carcinoma". Int. J. Cancer. 117 (2): 256–64. doi:10.1002/ijc.21200. PMID 15900605.
- Dumitriu IE, Baruah P, Bianchi ME; et al. (2005). "Requirement of HMGB1 and RAGE for the maturation of human plasmacytoid dendritic cells". Eur. J. Immunol. 35 (7): 2184–90. doi:10.1002/eji.200526066. PMID 15915542.
- Haslbeck KM, Friess U, Schleicher ED; et al. (2007). "The RAGE pathway in inflammatory myopathies and limb girdle muscular dystrophy". Acta Neuropathol. 110 (3): 247–54. doi:10.1007/s00401-005-1043-3. PMID 15986224.
- Ramprasad S, Radha V, Mathias RA; et al. (2007). "Rage gene promoter polymorphisms and diabetic retinopathy in a clinic-based population from South India". Eye (London, England). 21 (3): 395–401. doi:10.1038/sj.eye.6702239. PMID 16440015.
- Lindholm E, Bakhtadze E, Sjögren M; et al. (2007). "The -374 T/A polymorphism in the gene encoding RAGE is associated with diabetic nephropathy and retinopathy in type 1 diabetic patients". Diabetologia. 49 (11): 2745–55. doi:10.1007/s00125-006-0412-3. PMID 16969646.
- Dumitriu IE, Bianchi ME, Bacci M; et al. (2007). "The secretion of HMGB1 is required for the migration of maturing dendritic cells". J. Leukoc. Biol. 81 (1): 84–91. doi:10.1189/jlb.0306171. PMID 17035340.
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