RILP (gene)

Rab interacting lysosomal protein
File:PBB Protein RILP image.jpg PDB rendering based on 1yhn.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1yhn​
Identifiers
Symbols	RILP ; FLJ31193; PP10141
External IDs	Template:OMIM5 Template:MGI HomoloGene: 19596
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Rab interacting lysosomal protein, also known as RILP, is a human gene.

RILP, along with the GTPase RAB7 (MIM 602298), controls late endocytic transport.[supplied by OMIM]

Further reading

• Cantalupo G, Alifano P, Roberti V; et al. (2001). "Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes". EMBO J. 20 (4): 683–93. doi:10.1093/emboj/20.4.683. PMID 11179213.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bucci C, De Gregorio L, Bruni CB (2001). "Expression analysis and chromosomal assignment of PRA1 and RILP genes". Biochem. Biophys. Res. Commun. 286 (4): 815–9. doi:10.1006/bbrc.2001.5466. PMID 11520070.CS1 maint: Multiple names: authors list (link)
• Jordens I, Fernandez-Borja M, Marsman M; et al. (2002). "The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors". Curr. Biol. 11 (21): 1680–5. PMID 11696325.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang T, Hong W (2003). "Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rab-interacting lysosomal protein". Mol. Biol. Cell. 13 (12): 4317–32. doi:10.1091/mbc.E02-05-0280. PMID 12475955.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cardoso C, Leventer RJ, Ward HL; et al. (2003). "Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3". Am. J. Hum. Genet. 72 (4): 918–30. PMID 12621583.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Harrison RE, Bucci C, Vieira OV; et al. (2003). "Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP". Mol. Cell. Biol. 23 (18): 6494–506. PMID 12944476.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang T, Wong KK, Hong W (2004). "A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34". Mol. Biol. Cell. 15 (2): 815–26. doi:10.1091/mbc.E03-06-0413. PMID 14668488.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wan D, Gong Y, Qin W; et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMID 15498874.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wu M, Wang T, Loh E; et al. (2005). "Structural basis for recruitment of RILP by small GTPase Rab7". EMBO J. 24 (8): 1491–501. doi:10.1038/sj.emboj.7600643. PMID 15933719.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Colucci AM, Campana MC, Bellopede M, Bucci C (2005). "The Rab-interacting lysosomal protein, a Rab7 and Rab34 effector, is capable of self-interaction". Biochem. Biophys. Res. Commun. 334 (1): 128–33. doi:10.1016/j.bbrc.2005.06.067. PMID 15996637.CS1 maint: Multiple names: authors list (link)
• Shimojo M, Hersh LB (2006). "Characterization of the REST/NRSF-interacting LIM domain protein (RILP): localization and interaction with REST/NRSF". J. Neurochem. 96 (4): 1130–8. doi:10.1111/j.1471-4159.2005.03608.x. PMID 16417580.
• Marsman M, Jordens I, Rocha N; et al. (2006). "A splice variant of RILP induces lysosomal clustering independent of dynein recruitment". Biochem. Biophys. Res. Commun. 344 (3): 747–56. doi:10.1016/j.bbrc.2006.03.178. PMID 16631113.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Progida C, Spinosa MR, De Luca A, Bucci C (2006). "RILP interacts with the VPS22 component of the ESCRT-II complex". Biochem. Biophys. Res. Commun. 347 (4): 1074–9. doi:10.1016/j.bbrc.2006.07.007. PMID 16857164.CS1 maint: Multiple names: authors list (link)