ROBO2

Roundabout, axon guidance receptor, homolog 2 (Drosophila)
File:PBB Protein ROBO2 image.jpg PDB rendering based on 1uem.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1uem​, 1ujt​
Identifiers
Symbols	ROBO2 ; KIAA1568
External IDs	Template:OMIM5 Template:MGI HomoloGene: 43188
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE ROBO2 gnf1h07141 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Roundabout, axon guidance receptor, homolog 2 (Drosophila), also known as ROBO2, is a human gene.

Further reading

• Kidd T, Brose K, Mitchell KJ; et al. (1998). "Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors". Cell. 92 (2): 205–15. PMID 9458045.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brose K, Bland KS, Wang KH; et al. (1999). "Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance". Cell. 96 (6): 795–806. PMID 10102268.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nguyen Ba-Charvet KT, Brose K, Marillat V; et al. (1999). "Slit2-Mediated chemorepulsion and collapse of developing forebrain axons". Neuron. 22 (3): 463–73. PMID 10197527.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nagase T, Kikuno R, Nakayama M; et al. (2001). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. PMID 10997877.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nguyen Ba-Charvet KT, Brose K, Ma L; et al. (2001). "Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance". J. Neurosci. 21 (12): 4281–9. PMID 11404413.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Marillat V, Cases O, Nguyen-Ba-Charvet KT; et al. (2002). "Spatiotemporal expression patterns of slit and robo genes in the rat brain". J. Comp. Neurol. 442 (2): 130–55. PMID 11754167.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hivert B, Liu Z, Chuang CY; et al. (2003). "Robo1 and Robo2 are homophilic binding molecules that promote axonal growth". Mol. Cell. Neurosci. 21 (4): 534–45. PMID 12504588.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Grieshammer U, Le Ma , Plump AS; et al. (2004). "SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site". Dev. Cell. 6 (5): 709–17. PMID 15130495.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yue Y, Grossmann B, Galetzka D; et al. (2007). "Isolation and differential expression of two isoforms of the ROBO2/Robo2 axon guidance receptor gene in humans and mice". Genomics. 88 (6): 772–8. doi:10.1016/j.ygeno.2006.05.011. PMID 16829019.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lu W, van Eerde AM, Fan X; et al. (2007). "Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux". Am. J. Hum. Genet. 80 (4): 616–32. doi:10.1086/512735. PMID 17357069.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)