RRAS2

Related RAS viral (r-ras) oncogene homolog 2
File:PBB Protein RRAS2 image.jpg PDB rendering based on 2ery.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2ery​
Identifiers
Symbols	RRAS2 ; TC21
External IDs	Template:OMIM5 Template:MGI HomoloGene: 6945
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE RRAS2 212589 at tn.png
File:PBB GE RRAS2 208456 s at tn.png
File:PBB GE RRAS2 212590 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Related RAS viral (r-ras) oncogene homolog 2, also known as RRAS2, is a human gene.

Further reading

• Ehrhardt A, Ehrhardt GR, Guo X, Schrader JW (2002). "Ras and relatives--job sharing and networking keep an old family together". Exp. Hematol. 30 (10): 1089–106. PMID 12384139.CS1 maint: Multiple names: authors list (link)
• Drivas GT, Shih A, Coutavas E; et al. (1990). "Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line". Mol. Cell. Biol. 10 (4): 1793–8. PMID 2108320.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chan AM, Miki T, Meyers KA, Aaronson SA (1994). "A human oncogene of the RAS superfamily unmasked by expression cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 91 (16): 7558–62. PMID 8052619.CS1 maint: Multiple names: authors list (link)
• Rosário M, Paterson HF, Marshall CJ (1999). "Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells". EMBO J. 18 (5): 1270–9. doi:10.1093/emboj/18.5.1270. PMID 10064593.CS1 maint: Multiple names: authors list (link)
• Linnemann T, Geyer M, Jaitner BK; et al. (1999). "Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily". J. Biol. Chem. 274 (19): 13556–62. PMID 10224125.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ehrhardt GR, Leslie KB, Lee F; et al. (1999). "M-Ras, a widely expressed 29-kD homologue of p21 Ras: expression of a constitutively active mutant results in factor-independent growth of an interleukin-3-dependent cell line". Blood. 94 (7): 2433–44. PMID 10498616.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Movilla N, Crespo P, Bustelo XR (1999). "Signal transduction elements of TC21, an oncogenic member of the R-Ras subfamily of GTP-binding proteins". Oncogene. 18 (43): 5860–9. doi:10.1038/sj.onc.1202968. PMID 10557073.CS1 maint: Multiple names: authors list (link)
• Ohba Y, Mochizuki N, Yamashita S; et al. (2000). "Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3". J. Biol. Chem. 275 (26): 20020–6. doi:10.1074/jbc.M000981200. PMID 10777492.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Figueroa C, Taylor J, Vojtek AB (2001). "Prenylated Rab acceptor protein is a receptor for prenylated small GTPases". J. Biol. Chem. 276 (30): 28219–25. doi:10.1074/jbc.M101763200. PMID 11335720.CS1 maint: Multiple names: authors list (link)
• Murphy GA, Graham SM, Morita S; et al. (2002). "Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation". J. Biol. Chem. 277 (12): 9966–75. doi:10.1074/jbc.M109059200. PMID 11788587.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rong R, He Q, Liu Y; et al. (2002). "TC21 mediates transformation and cell survival via activation of phosphatidylinositol 3-kinase/Akt and NF-kappaB signaling pathway". Oncogene. 21 (7): 1062–70. doi:10.1038/sj.onc.1205154. PMID 11850823.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ortiz-Vega S, Khokhlatchev A, Nedwidek M; et al. (2002). "The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1". Oncogene. 21 (9): 1381–90. doi:10.1038/sj.onc.1205192. PMID 11857081.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yuryev A, Wennogle LP (2003). "Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis". Genomics. 81 (2): 112–25. PMID 12620389.
• Mitin NY, Ramocki MB, Zullo AJ; et al. (2004). "Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization". J. Biol. Chem. 279 (21): 22353–61. doi:10.1074/jbc.M312867200. PMID 15031288.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kho Y, Kim SC, Jiang C; et al. (2004). "A tagging-via-substrate technology for detection and proteomics of farnesylated proteins". Proc. Natl. Acad. Sci. U.S.A. 101 (34): 12479–84. doi:10.1073/pnas.0403413101. PMID 15308774.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Suzuki Y, Yamashita R, Shirota M; et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Barrios-Rodiles M, Brown KR, Ozdamar B; et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)