SMARCC1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Identifiers
Symbols	SMARCC1 ; BAF155; CRACC1; Rsc8; SRG3; SWI3
External IDs	Template:OMIM5 Template:MGI HomoloGene: 68296
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SMARCC1 201075 s at tn.png
File:PBB GE SMARCC1 201072 s at tn.png
File:PBB GE SMARCC1 201073 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1, also known as SMARCC1, is a human gene.

The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.

Further reading

• Wang W, Xue Y, Zhou S; et al. (1996). "Diversity and specialization of mammalian SWI/SNF complexes". Genes Dev. 10 (17): 2117–30. PMID 8804307.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.CS1 maint: Multiple names: authors list (link)
• Wang W, Côté J, Xue Y; et al. (1996). "Purification and biochemical heterogeneity of the mammalian SWI-SNF complex". EMBO J. 15 (19): 5370–82. PMID 8895581.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fryer CJ, Archer TK (1998). "Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex". Nature. 393 (6680): 88–91. doi:10.1038/30032. PMID 9590696.
• Ring HZ, Vameghi-Meyers V, Wang W; et al. (1998). "Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome". Genomics. 51 (1): 140–3. doi:10.1006/geno.1998.5343. PMID 9693044.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cho H, Orphanides G, Sun X; et al. (1998). "A human RNA polymerase II complex containing factors that modify chromatin structure". Mol. Cell. Biol. 18 (9): 5355–63. PMID 9710619.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sif S, Stukenberg PT, Kirschner MW, Kingston RE (1998). "Mitotic inactivation of a human SWI/SNF chromatin remodeling complex". Genes Dev. 12 (18): 2842–51. PMID 9744861.CS1 maint: Multiple names: authors list (link)
• Shanahan F, Seghezzi W, Parry D; et al. (1999). "Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest". Mol. Cell. Biol. 19 (2): 1460–9. PMID 9891079.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Phelan ML, Sif S, Narlikar GJ, Kingston RE (1999). "Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits". Mol. Cell. 3 (2): 247–53. PMID 10078207.CS1 maint: Multiple names: authors list (link)
• Kowenz-Leutz E, Leutz A (2000). "A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes". Mol. Cell. 4 (5): 735–43. PMID 10619021.
• Bochar DA, Wang L, Beniya H; et al. (2000). "BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer". Cell. 102 (2): 257–65. PMID 10943845.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kadam S, McAlpine GS, Phelan ML; et al. (2000). "Functional selectivity of recombinant mammalian SWI/SNF subunits". Genes Dev. 14 (19): 2441–51. PMID 11018012.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xue Y, Canman JC, Lee CS; et al. (2001). "The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes". Proc. Natl. Acad. Sci. U.S.A. 97 (24): 13015–20. doi:10.1073/pnas.240208597. PMID 11078522.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sif S, Saurin AJ, Imbalzano AN, Kingston RE (2001). "Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes". Genes Dev. 15 (5): 603–18. doi:10.1101/gad.872801. PMID 11238380.CS1 maint: Multiple names: authors list (link)
• Otsuki T, Furukawa Y, Ikeda K; et al. (2002). "Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex". Hum. Mol. Genet. 10 (23): 2651–60. PMID 11726552.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kato H, Tjernberg A, Zhang W; et al. (2002). "SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones". J. Biol. Chem. 277 (7): 5498–505. doi:10.1074/jbc.M108702200. PMID 11734557.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nie Z, Yan Z, Chen EH; et al. (2003). "Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner". Mol. Cell. Biol. 23 (8): 2942–52. PMID 12665591.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kitagawa H, Fujiki R, Yoshimura K; et al. (2003). "The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome". Cell. 113 (7): 905–17. PMID 12837248.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hsiao PW, Fryer CJ, Trotter KW; et al. (2003). "BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation". Mol. Cell. Biol. 23 (17): 6210–20. PMID 12917342.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)