SYNE2
Spectrin repeat containing, nuclear envelope 2 | |||||||||
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Identifiers | |||||||||
Symbols | SYNE2 ; DKFZP434H2235; DKFZp686E01115; DKFZp686H1931; FLJ11014; FLJ43727; FLJ45710; FLJ46790; KIAA1011; NUA; NUANCE; Nesprin-2; SYNE-2 | ||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 56700 | ||||||||
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RNA expression pattern | |||||||||
File:PBB GE SYNE2 202761 s at tn.png | |||||||||
More reference expression data | |||||||||
Orthologs | |||||||||
Template:GNF Ortholog box | |||||||||
Species | Human | Mouse | |||||||
Entrez | n/a | n/a | |||||||
Ensembl | n/a | n/a | |||||||
UniProt | n/a | n/a | |||||||
RefSeq (mRNA) | n/a | n/a | |||||||
RefSeq (protein) | n/a | n/a | |||||||
Location (UCSC) | n/a | n/a | |||||||
PubMed search | n/a | n/a |
Spectrin repeat containing, nuclear envelope 2, also known as SYNE2, is a human gene.[1]
References
Further reading
- Nakajima D, Okazaki N, Yamakawa H; et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. PMID 12168954.
- Nagase T, Ishikawa K, Suyama M; et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. PMID 10231032.
- Apel ED, Lewis RM, Grady RM, Sanes JR (2000). "Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction". J. Biol. Chem. 275 (41): 31986–95. doi:10.1074/jbc.M004775200. PMID 10878022.
- Wiemann S, Weil B, Wellenreuther R; et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
- Zhang Q, Skepper JN, Yang F; et al. (2002). "Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues". J. Cell. Sci. 114 (Pt 24): 4485–98. PMID 11792814.
- Zhen YY, Libotte T, Munck M; et al. (2003). "NUANCE, a giant protein connecting the nucleus and actin cytoskeleton". J. Cell. Sci. 115 (Pt 15): 3207–22. PMID 12118075.
- Zhang Q, Ragnauth C, Greener MJ; et al. (2003). "The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300". Genomics. 80 (5): 473–81. PMID 12408964.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Heilig R, Eckenberg R, Petit JL; et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. doi:10.1038/nature01348. PMID 12508121.
- Schirmer EC, Florens L, Guan T; et al. (2003). "Nuclear membrane proteins with potential disease links found by subtractive proteomics". Science. 301 (5638): 1380–2. doi:10.1126/science.1088176. PMID 12958361.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Zhang Q, Ragnauth CD, Skepper JN; et al. (2005). "Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle". J. Cell. Sci. 118 (Pt 4): 673–87. doi:10.1242/jcs.01642. PMID 15671068.
- Cheng J, Kapranov P, Drenkow J; et al. (2005). "Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution". Science. 308 (5725): 1149–54. doi:10.1126/science.1108625. PMID 15790807.
- Libotte T, Zaim H, Abraham S; et al. (2005). "Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope". Mol. Biol. Cell. 16 (7): 3411–24. doi:10.1091/mbc.E04-11-1009. PMID 15843432.
- Padmakumar VC, Libotte T, Lu W; et al. (2005). "The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope". J. Cell. Sci. 118 (Pt 15): 3419–30. doi:10.1242/jcs.02471. PMID 16079285.
- Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
- Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Wheeler MA, Davies JD, Zhang Q; et al. (2007). "Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy". Exp. Cell Res. 313 (13): 2845–57. doi:10.1016/j.yexcr.2007.03.025. PMID 17462627.
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