TCF7
Transcription factor 7 (T-cell specific, HMG-box) | |||||||||||||
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File:PBB Protein TCF7 image.jpg PDB rendering based on 2lef. | |||||||||||||
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Identifiers | |||||||||||||
Symbols | TCF7 ; MGC47735; TCF-1 | ||||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 2410 | ||||||||||||
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RNA expression pattern | |||||||||||||
File:PBB GE TCF7 205254 x at tn.png | |||||||||||||
File:PBB GE TCF7 205255 x at tn.png | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Template:GNF Ortholog box | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | n/a | n/a | |||||||||||
Ensembl | n/a | n/a | |||||||||||
UniProt | n/a | n/a | |||||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||||
RefSeq (protein) | n/a | n/a | |||||||||||
Location (UCSC) | n/a | n/a | |||||||||||
PubMed search | n/a | n/a |
Transcription factor 7 (T-cell specific, HMG-box), also known as TCF7, is a human gene.[1]
References
Further reading
- van de Wetering M, Oosterwegel M, Holstege F; et al. (1992). "The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization". J. Biol. Chem. 267 (12): 8530–6. PMID 1569101.
- van de Wetering M, Oosterwegel M, Dooijes D, Clevers H (1991). "Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box". EMBO J. 10 (1): 123–32. PMID 1989880.
- Castrop J, van Wichen D, Koomans-Bitter M; et al. (1995). "The human TCF-1 gene encodes a nuclear DNA-binding protein uniquely expressed in normal and neoplastic T-lineage lymphocytes". Blood. 86 (8): 3050–9. PMID 7579399.
- Mayer K, Wolff E, Clevers H, Ballhausen WG (1995). "The human high mobility group (HMG)-box transcription factor TCF-1: novel isoforms due to alternative splicing and usage of a new exon IXA". Biochim. Biophys. Acta. 1263 (2): 169–72. PMID 7640309.
- Van de Wetering M, Castrop J, Korinek V, Clevers H (1996). "Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties". Mol. Cell. Biol. 16 (3): 745–52. PMID 8622675.
- Korinek V, Barker N, Willert K; et al. (1998). "Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse". Mol. Cell. Biol. 18 (3): 1248–56. PMID 9488439.
- Roose J, Molenaar M, Peterson J; et al. (1998). "The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors". Nature. 395 (6702): 608–12. doi:10.1038/26989. PMID 9783587.
- Roose J, Huls G, van Beest M; et al. (1999). "Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1". Science. 285 (5435): 1923–6. PMID 10489374.
- Brantjes H, Roose J, van De Wetering M, Clevers H (2001). "All Tcf HMG box transcription factors interact with Groucho-related co-repressors". Nucleic Acids Res. 29 (7): 1410–9. PMID 11266540.
- Batlle E, Henderson JT, Beghtel H; et al. (2002). "Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB". Cell. 111 (2): 251–63. PMID 12408869.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Noble JA, White AM, Lazzeroni LC; et al. (2003). "A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes". Diabetes. 52 (6): 1579–82. PMID 12765974.
- Ioannidis V, Kunz B, Tanamachi DM; et al. (2003). "Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1". J. Immunol. 171 (2): 769–75. PMID 12847244.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Smit L, Baas A, Kuipers J; et al. (2004). "Wnt activates the Tak1/Nemo-like kinase pathway". J. Biol. Chem. 279 (17): 17232–40. doi:10.1074/jbc.M307801200. PMID 14960582.
- Smith SS, Patterson T, Pauza ME (2005). "Transgenic Ly-49A inhibits antigen-driven T cell activation and delays diabetes". J. Immunol. 174 (7): 3897–905. PMID 15778344.
- Willinger T, Freeman T, Herbert M; et al. (2006). "Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo". J. Immunol. 176 (3): 1439–46. PMID 16424171.
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