TIMM13

Translocase of inner mitochondrial membrane 13 homolog (yeast)
Identifiers
Symbols	TIMM13 ; TIM13; TIM13B; TIMM13A; TIMM13B; ppv1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 40846
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE TIMM13 218188 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Translocase of inner mitochondrial membrane 13 homolog (yeast), also known as TIMM13, is a human gene.

This gene encodes a translocase with similarity to yeast mitochondrial proteins that are involved in the import of metabolite transporters from the cytoplasm and into the mitochondrial inner membrane. The encoded protein and the TIMM8a protein form a 70 kDa complex in the intermembrane space. This gene is in a head-to-tail orientation with the gene for lamin B2.

Further reading

• Rehling P, Wiedemann N, Pfanner N, Truscott KN (2001). "The mitochondrial import machinery for preproteins". Crit. Rev. Biochem. Mol. Biol. 36 (3): 291–336. PMID 11450972.CS1 maint: Multiple names: authors list (link)
• Paschen SA, Neupert W (2002). "Protein import into mitochondria". IUBMB Life. 52 (3–5): 101–12. PMID 11798021.
• Neupert W, Brunner M (2002). "The protein import motor of mitochondria". Nat. Rev. Mol. Cell Biol. 3 (8): 555–65. doi:10.1038/nrm878. PMID 12154367.
• Jensen RE, Dunn CD (2002). "Protein import into and across the mitochondrial inner membrane: role of the TIM23 and TIM22 translocons". Biochim. Biophys. Acta. 1592 (1): 25–34. PMID 12191765.
• Jin H, Kendall E, Freeman TC; et al. (2000). "The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins". Genomics. 61 (3): 259–67. doi:10.1006/geno.1999.5966. PMID 10552927.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bauer MF, Rothbauer U, Mühlenbein N; et al. (2000). "The mitochondrial TIM22 preprotein translocase is highly conserved throughout the eukaryotic kingdom". FEBS Lett. 464 (1–2): 41–7. PMID 10611480.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Paschen SA, Rothbauer U, Káldi K; et al. (2001). "The role of the TIM8-13 complex in the import of Tim23 into mitochondria". EMBO J. 19 (23): 6392–400. doi:10.1093/emboj/19.23.6392. PMID 11101512.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rothbauer U, Hofmann S, Mühlenbein N; et al. (2001). "Role of the deafness dystonia peptide 1 (DDP1) in import of human Tim23 into the inner membrane of mitochondria". J. Biol. Chem. 276 (40): 37327–34. doi:10.1074/jbc.M105313200. PMID 11489896.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Roesch K, Curran SP, Tranebjaerg L, Koehler CM (2002). "Human deafness dystonia syndrome is caused by a defect in assembly of the DDP1/TIMM8a-TIMM13 complex". Hum. Mol. Genet. 11 (5): 477–86. PMID 11875042.CS1 maint: Multiple names: authors list (link)
• Chacinska A, Pfanner N, Meisinger C (2003). "How mitochondria import hydrophilic and hydrophobic proteins". Trends Cell Biol. 12 (7): 299–303. PMID 12185844.CS1 maint: Multiple names: authors list (link)
• Curran SP, Leuenberger D, Schmidt E, Koehler CM (2002). "The role of the Tim8p-Tim13p complex in a conserved import pathway for mitochondrial polytopic inner membrane proteins". J. Cell Biol. 158 (6): 1017–27. doi:10.1083/jcb.200205124. PMID 12221072.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Roesch K, Hynds PJ, Varga R; et al. (2005). "The calcium-binding aspartate/glutamate carriers, citrin and aralar1, are new substrates for the DDP1/TIMM8a-TIMM13 complex". Hum. Mol. Genet. 13 (18): 2101–11. doi:10.1093/hmg/ddh217. PMID 15254020.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)