TMEFF2

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Transmembrane protein with EGF-like and two follistatin-like domains 2
Identifiers
Symbols TMEFF2 ; TR; HPP1; TENB2; TPEF
External IDs Template:OMIM5 Template:MGI HomoloGene9417
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Transmembrane protein with EGF-like and two follistatin-like domains 2, also known as TMEFF2, is a human gene.[1]


References

  1. "Entrez Gene: TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
  • Uchida T, Wada K, Akamatsu T; et al. (2000). "A novel epidermal growth factor-like molecule containing two follistatin modules stimulates tyrosine phosphorylation of erbB-4 in MKN28 gastric cancer cells". Biochem. Biophys. Res. Commun. 266 (2): 593–602. doi:10.1006/bbrc.1999.1873. PMID 10600548.
  • Horie M, Mitsumoto Y, Kyushiki H; et al. (2000). "Identification and characterization of TMEFF2, a novel survival factor for hippocampal and mesencephalic neurons". Genomics. 67 (2): 146–52. doi:10.1006/geno.2000.6228. PMID 10903839.
  • Liang G, Robertson KD, Talmadge C; et al. (2000). "The gene for a novel transmembrane protein containing epidermal growth factor and follistatin domains is frequently hypermethylated in human tumor cells". Cancer Res. 60 (17): 4907–12. PMID 10987305.
  • Young J, Biden KG, Simms LA; et al. (2001). "HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers". Proc. Natl. Acad. Sci. U.S.A. 98 (1): 265–70. doi:10.1073/pnas.011415298. PMID 11120884.
  • Glynne-Jones E, Harper ME, Seery LT; et al. (2001). "TENB2, a proteoglycan identified in prostate cancer that is associated with disease progression and androgen independence". Int. J. Cancer. 94 (2): 178–84. PMID 11668495.
  • Shibata DM, Sato F, Mori Y; et al. (2002). "Hypermethylation of HPP1 is associated with hMLH1 hypermethylation in gastric adenocarcinomas". Cancer Res. 62 (20): 5637–40. PMID 12384516.
  • Sato F, Shibata D, Harpaz N; et al. (2003). "Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma". Cancer Res. 62 (23): 6820–2. PMID 12460892.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Gery S, Koeffler HP (2003). "Repression of the TMEFF2 promoter by c-Myc". J. Mol. Biol. 328 (5): 977–83. PMID 12729735.
  • Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Sabbioni S, Miotto E, Veronese A; et al. (2004). "Multigene methylation analysis of gastrointestinal tumors: TPEF emerges as a frequent tumor-specific aberrantly methylated marker that can be detected in peripheral blood". Mol. Diagn. 7 (3–4): 201–7. PMID 15068392.
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMID 15340161.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Hillier LW, Graves TA, Fulton RS; et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
  • Schulmann K, Sterian A, Berki A; et al. (2005). "Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk". Oncogene. 24 (25): 4138–48. doi:10.1038/sj.onc.1208598. PMID 15824739.
  • Suzuki M, Shigematsu H, Shames DS; et al. (2005). "DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers". Br. J. Cancer. 93 (9): 1029–37. doi:10.1038/sj.bjc.6602837. PMID 16234815.
  • Otsuki T, Ota T, Nishikawa T; et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.

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