TNNI2
Troponin I type 2 (skeletal, fast) | |||||||||||||
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File:PBB Protein TNNI2 image.jpg PDB rendering based on 1a2x. | |||||||||||||
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Identifiers | |||||||||||||
Symbols | TNNI2 ; AMCD2B; DA2B; FSSV | ||||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 37752 | ||||||||||||
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RNA expression pattern | |||||||||||||
File:PBB GE TNNI2 206393 at tn.png | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Template:GNF Ortholog box | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | n/a | n/a | |||||||||||
Ensembl | n/a | n/a | |||||||||||
UniProt | n/a | n/a | |||||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||||
RefSeq (protein) | n/a | n/a | |||||||||||
Location (UCSC) | n/a | n/a | |||||||||||
PubMed search | n/a | n/a |
Troponin I type 2 (skeletal, fast), also known as TNNI2, is a human gene.[1]
References
Further reading
- Kinoshita S, Adachi W, Sotozono C; et al. (2001). "Characteristics of the human ocular surface epithelium". Progress in retinal and eye research. 20 (5): 639–73. PMID 11470454.
- Wade R, Eddy R, Shows TB, Kedes L (1990). "cDNA sequence, tissue-specific expression, and chromosomal mapping of the human slow-twitch skeletal muscle isoform of troponin I.". Genomics. 7 (3): 346–57. PMID 2365354.
- Huang TS, Bylund DB, Stull JT, Krebs EG (1974). "The amino acid sequences of the phosphorylated sites in troponin-I from rabbit skeletal muscle". FEBS Lett. 42 (3): 249–52. PMID 4369265.
- Moir AJ, Ordidge M, Grand RJ; et al. (1983). "Studies of the interaction of troponin I with proteins of the I-filament and calmodulin". Biochem. J. 209 (2): 417–26. PMID 6847627.
- Grand RJ, Levine BA, Perry SV (1982). "Proton-magnetic-resonance studies on the interaction of rabbit skeletal-muscle troponin I with troponin C and actin". Biochem. J. 203 (1): 61–8. PMID 7103951.
- Chong PC, Hodges RS (1982). "Photochemical cross-linking between rabbit skeletal troponin subunits. Troponin I-troponin T interactions". J. Biol. Chem. 257 (19): 11667–72. PMID 7118902.
- Zhu L, Perez-Alvarado G, Wade R (1994). "Sequencing of a cDNA encoding the human fast-twitch skeletal muscle isoform of troponin I.". Biochim. Biophys. Acta. 1217 (3): 338–40. PMID 8148383.
- Lanfranchi G, Muraro T, Caldara F; et al. (1996). "Identification of 4370 expressed sequence tags from a 3'-end-specific cDNA library of human skeletal muscle by DNA sequencing and filter hybridization". Genome Res. 6 (1): 35–42. PMID 8681137.
- Jha PK, Leavis PC, Sarkar S (1997). "Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system". Biochemistry. 35 (51): 16573–80. doi:10.1021/bi9622433. PMID 8987992.
- Tiso N, Rampoldi L, Pallavicini A; et al. (1997). "Fine mapping of five human skeletal muscle genes: alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast". Biochem. Biophys. Res. Commun. 230 (2): 347–50. doi:10.1006/bbrc.1996.5958. PMID 9016781.
- Stefancsik R, Jha PK, Sarkar S (1998). "Identification and mutagenesis of a highly conserved domain in troponin T responsible for troponin I binding: potential role for coiled coil interaction". Proc. Natl. Acad. Sci. U.S.A. 95 (3): 957–62. PMID 9448267.
- Vassylyev DG, Takeda S, Wakatsuki S; et al. (1998). "Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution". Proc. Natl. Acad. Sci. U.S.A. 95 (9): 4847–52. PMID 9560191.
- Jha PK, Sarkar S (1998). "A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I.". Biochemistry. 37 (35): 12253–60. doi:10.1021/bi980025z. PMID 9724539.
- Moses MA, Wiederschain D, Wu I; et al. (1999). "Troponin I is present in human cartilage and inhibits angiogenesis". Proc. Natl. Acad. Sci. U.S.A. 96 (6): 2645–50. PMID 10077564.
- Mullen AJ, Barton PJ (2000). "Structural characterization of the human fast skeletal muscle troponin I gene (TNNI2)". Gene. 242 (1–2): 313–20. PMID 10721725.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Sung SS, Brassington AM, Grannatt K; et al. (2003). "Mutations in genes encoding fast-twitch contractile proteins cause distal arthrogryposis syndromes". Am. J. Hum. Genet. 72 (3): 681–90. PMID 12592607.
- Li Q, Liu Y, Shen PY; et al. (2003). "Troponin I binds polycystin-L and inhibits its calcium-induced channel activation". Biochemistry. 42 (24): 7618–25. doi:10.1021/bi034210a. PMID 12809519.
- Thijssen VL, Ausma J, Gorza L; et al. (2005). "Troponin I isoform expression in human and experimental atrial fibrillation". Circulation. 110 (7): 770–5. doi:10.1161/01.CIR.0000138849.03311.C6. PMID 15289369.
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