TNNT1

Troponin T type 1 (skeletal, slow)
Identifiers
Symbols	TNNT1 ; ANM; MGC104241
External IDs	Template:OMIM5 Template:MGI HomoloGene: 20704
Gene ontology Molecular function Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE TNNT1 213201 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Troponin T type 1 (skeletal, slow), also known as TNNT1, is a human gene.

Further reading

• Nadal-Ginard B, Mahdavi V (1990). "Molecular basis of cardiac performance. Plasticity of the myocardium generated through protein isoform switches". J. Clin. Invest. 84 (6): 1693–700. PMID 2687327.
• Wu AH, Ford L (1999). "Release of cardiac troponin in acute coronary syndromes: ischemia or necrosis?". Clin. Chim. Acta. 284 (2): 161–74. PMID 10451243.
• Novelli G, Gennarelli M, Zelano G; et al. (1993). "Polymerase chain reaction in the detection of mRNA transcripts from the slow skeletal troponin T (TNNT1) gene in myotonic dystrophy and normal muscle". Cell Biochem. Funct. 10 (4): 251–6. doi:10.1002/cbf.290100407. PMID 1473264.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Samson F, de Jong PJ, Trask BJ; et al. (1992). "Assignment of the human slow skeletal troponin T gene to 19q13.4 using somatic cell hybrids and fluorescence in situ hybridization analysis". Genomics. 13 (4): 1374–5. PMID 1505979.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gahlmann R, Troutt AB, Wade RP; et al. (1987). "Alternative splicing generates variants in important functional domains of human slow skeletal troponin T.". J. Biol. Chem. 262 (33): 16122–6. PMID 2824479.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Heeley DH, Golosinska K, Smillie LB (1987). "The effects of troponin T fragments T1 and T2 on the binding of nonpolymerizable tropomyosin to F-actin in the presence and absence of troponin I and troponin C.". J. Biol. Chem. 262 (21): 9971–8. PMID 3611073.CS1 maint: Multiple names: authors list (link)
• Pearlstone JR, Smillie LB (1983). "Effects of troponin-I plus-C on the binding of troponin-T and its fragments to alpha-tropomyosin. Ca2+ sensitivity and cooperativity". J. Biol. Chem. 258 (4): 2534–42. PMID 6822572.
• Samson F, Mesnard L, Mihovilovic M; et al. (1994). "A new human slow skeletal troponin T (TnTs) mRNA isoform derived from alternative splicing of a single gene". Biochem. Biophys. Res. Commun. 199 (2): 841–7. doi:10.1006/bbrc.1994.1305. PMID 8135831.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Novelli G, Gennarelli M, Sangiuolo F; et al. (1993). "Isolation and cloning by a polymerase chain reaction of a genomic DNA fragment of the human slow skeletal troponin (TNNT1) gene". Cell Biochem. Funct. 11 (3): 187–91. doi:10.1002/cbf.290110306. PMID 8403232.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jha PK, Leavis PC, Sarkar S (1997). "Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system". Biochemistry. 35 (51): 16573–80. doi:10.1021/bi9622433. PMID 8987992.CS1 maint: Multiple names: authors list (link)
• Stefancsik R, Jha PK, Sarkar S (1998). "Identification and mutagenesis of a highly conserved domain in troponin T responsible for troponin I binding: potential role for coiled coil interaction". Proc. Natl. Acad. Sci. U.S.A. 95 (3): 957–62. PMID 9448267.CS1 maint: Multiple names: authors list (link)
• Jha PK, Sarkar S (1998). "A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I.". Biochemistry. 37 (35): 12253–60. doi:10.1021/bi980025z. PMID 9724539.
• Barton PJ, Cullen ME, Townsend PJ; et al. (1999). "Close physical linkage of human troponin genes: organization, sequence, and expression of the locus encoding cardiac troponin I and slow skeletal troponin T.". Genomics. 57 (1): 102–9. doi:10.1006/geno.1998.5702. PMID 10191089.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mukherjea P, Tong L, Seidman JG; et al. (1999). "Altered regulatory function of two familial hypertrophic cardiomyopathy troponin T mutants". Biochemistry. 38 (40): 13296–301. PMID 10529204.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yuasa K, Michibata H, Omori K, Yanaka N (2000). "A novel interaction of cGMP-dependent protein kinase I with troponin T.". J. Biol. Chem. 274 (52): 37429–34. PMID 10601315.CS1 maint: Multiple names: authors list (link)
• Johnston JJ, Kelley RI, Crawford TO; et al. (2000). "A novel nemaline myopathy in the Amish caused by a mutation in troponin T1". Am. J. Hum. Genet. 67 (4): 814–21. PMID 10952871.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Schmidtmann A, Lohmann K, Jaquet K (2002). "The interaction of the bisphosphorylated N-terminal arm of cardiac troponin I-A 31P-NMR study". FEBS Lett. 513 (2–3): 289–93. PMID 11904166.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)