Thymosin beta-4, Y-chromosomal
Thymosin, beta 4, Y-linked | |||||||||||
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Identifiers | |||||||||||
Symbols | TMSB4Y ; MGC26307; TB4Y | ||||||||||
External IDs | Template:OMIM5 | ||||||||||
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RNA expression pattern | |||||||||||
File:PBB GE TMSB4Y 206769 at tn.png | |||||||||||
More reference expression data | |||||||||||
Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
Thymosin, beta 4, Y-linked, also known as TMSB4Y, is a human gene.[1]
This gene lies within the male specific region of chromosome Y. Its homolog on chromosome X escapes X inactivation and encodes an actin sequestering protein.[1]
References
Further reading
- Yu FX, Lin SC, Morrison-Bogorad M; et al. (1993). "Thymosin beta 10 and thymosin beta 4 are both actin monomer sequestering proteins". J. Biol. Chem. 268 (1): 502–9. PMID 8416954.
- Li X, Zimmerman A, Copeland NG; et al. (1997). "The mouse thymosin beta 4 gene: structure, promoter identification, and chromosome localization". Genomics. 32 (3): 388–94. doi:10.1006/geno.1996.0133. PMID 8838802.
- Lahn BT, Page DC (1997). "Functional coherence of the human Y chromosome". Science. 278 (5338): 675–80. PMID 9381176.
- "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. PMID 9847074.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Skaletsky H, Kuroda-Kawaguchi T, Minx PJ; et al. (2003). "The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes". Nature. 423 (6942): 825–37. doi:10.1038/nature01722. PMID 12815422.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Torikai H, Akatsuka Y, Miyazaki M; et al. (2005). "A novel HLA-A*3303-restricted minor histocompatibility antigen encoded by an unconventional open reading frame of human TMSB4Y gene". J. Immunol. 173 (11): 7046–54. PMID 15557202.
- Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
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