USP5
Ubiquitin specific peptidase 5 (isopeptidase T) | |||||||||||||
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File:PBB Protein USP5 image.jpg PDB rendering based on 2dag. | |||||||||||||
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Identifiers | |||||||||||||
Symbols | USP5 ; ISOT | ||||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 55758 | ||||||||||||
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RNA expression pattern | |||||||||||||
File:PBB GE USP5 206031 s at tn.png | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Template:GNF Ortholog box | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | n/a | n/a | |||||||||||
Ensembl | n/a | n/a | |||||||||||
UniProt | n/a | n/a | |||||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||||
RefSeq (protein) | n/a | n/a | |||||||||||
Location (UCSC) | n/a | n/a | |||||||||||
PubMed search | n/a | n/a |
Ubiquitin specific peptidase 5 (isopeptidase T), also known as USP5, is a human gene.[1]
References
Further reading
- D'Andrea A, Pellman D (1999). "Deubiquitinating enzymes: a new class of biological regulators". Crit. Rev. Biochem. Mol. Biol. 33 (5): 337–52. PMID 9827704.
- Puente XS, Sánchez LM, Overall CM, López-Otín C (2003). "Human and mouse proteases: a comparative genomic approach". Nat. Rev. Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346.
- Falquet L, Paquet N, Frutiger S; et al. (1996). "cDNA cloning of a human 100 kDa de-ubiquitinating enzyme: the 100 kDa human de-ubiquitinase belongs to the ubiquitin C-terminal hydrolase family 2 (UCH2)". FEBS Lett. 376 (3): 233–7. PMID 7498549.
- Wilkinson KD, Tashayev VL, O'Connor LB; et al. (1995). "Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T.". Biochemistry. 34 (44): 14535–46. PMID 7578059.
- Falquet L, Paquet N, Frutiger S; et al. (1995). "A human de-ubiquitinating enzyme with both isopeptidase and peptidase activities in vitro". FEBS Lett. 359 (1): 73–7. PMID 7851534.
- Ansari-Lari MA, Muzny DM, Lu J; et al. (1996). "A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13". Genome Res. 6 (4): 314–26. PMID 8723724.
- Ansari-Lari MA, Shen Y, Muzny DM; et al. (1997). "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination". Genome Res. 7 (3): 268–80. PMID 9074930.
- Suzuki Y, Tsunoda T, Sese J; et al. (2001). "Identification and characterization of the potential promoter regions of 1031 kinds of human genes". Genome Res. 11 (5): 677–84. doi:10.1101/gr.164001. PMID 11337467.
- Engidawork E, Juranville JF, Fountoulakis M; et al. (2002). "Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal Down syndrome". J. Neural Transm. Suppl. (61): 117–30. PMID 11771738.
- Gabriel JM, Lacombe T, Carobbio S; et al. (2002). "Zinc is required for the catalytic activity of the human deubiquitinating isopeptidase T.". Biochemistry. 41 (46): 13755–66. PMID 12427038.
- Lacombe T, Gabriel JM (2002). "Further characterization of the putative human isopeptidase T catalytic site". FEBS Lett. 531 (3): 469–74. PMID 12435595.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Anderson NL, Polanski M, Pieper R; et al. (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources". Mol. Cell Proteomics. 3 (4): 311–26. doi:10.1074/mcp.M300127-MCP200. PMID 14718574.
- Brandenberger R, Wei H, Zhang S; et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
- Colland F, Jacq X, Trouplin V; et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Reyes-Turcu FE, Horton JR, Mullally JE; et al. (2006). "The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin". Cell. 124 (6): 1197–208. doi:10.1016/j.cell.2006.02.038. PMID 16564012.
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