Ameloblastoma pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Ameloblastoma Microchapters
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Overview
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Pathophysiology
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Differentiating Ameloblastoma from other Diseases
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Pathophysiology

Microscopic Pathology

Histopathology will show cells that have the tendency to move the nucleus away from the basement membrane. This process is referred to as "Reverse Polarization". The follicular type will have outer arrangement of columnar or palisaded ameloblast like cells and inner zone of triangular shaped cells resembling stellate reticulum in bell stage. The central cells sometimes degenerate to form central microcysts. The plexiform type has epithelium that proliferates in a "Fish Net Pattern".

Histologic Variants

• Desmoplastic ameloblastoma
• Granular cell variant
• Basal cell variant